The Immune Response to Implanted Materials and Devices The Impact of
This book provides a comprehensive overview of the cascade of events activated in the body following the implant of biomaterials and devices. It is one of the first books to shed light on the role of the host immune response on therapeutic efficacy of an
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The Immune Response to Implanted Materials and Devices The Impact of the Immune System on the Success of an Implant
The Immune Response to Implanted Materials and Devices
Bruna Corradetti Editor
The Immune Response to Implanted Materials and Devices The Impact of the Immune System on the Success of an Implant
Editor Bruna Corradetti Department of Life and Environmental Sciences Marche Polytechnic University Ancona, Italy
ISBN 978-3-319-45431-3 ISBN 978-3-319-45433-7 DOI 10.1007/978-3-319-45433-7
(eBook)
Library of Congress Control Number: 2016948732 © Springer International Publishing Switzerland 2017 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper This Springer imprint is published by Springer Nature The registered company is Springer International Publishing AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland
Foreword
In the powerfully emerging world of smart, or functional materials, I cannot imagine a class with greater potential impact on healthcare and societal benefits than biomaterials with an ability to modulate inflammatory response—precisely the subject focus of this exceptionally timely monograph edited by Dr. Bruna Corradetti. All materials for use in healthcare elicit an inflammatory response, bar none; but exactly as inflammation can be a fundamental step in a healing process, or a formidable foe, if frustrated into a chronic manifestation, this biological response to a material interface can be essentially helpful, or profoundly detrimental. Materials technology, and our understanding of the many facets of inflammation, has finally reached a point of sufficient maturity and convergence, to make it possible, for biomaterials to be designed so as to elicit a beneficial, or at least a functionally neutral response from the biology with which they contact. The downstream vision from this exciting vantage point potentially portends transformational breakthroughs in multiple domains of healthcare, ranging from
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