The impact of overactive bladder on health-related quality of life in Korea: based on the results of a Korean Community

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The impact of overactive bladder on health‑related quality of life in Korea: based on the results of a Korean Community Health Survey Sang‑Kyu Kim1   · Seon‑Ha Kim2  Accepted: 11 November 2020 © Springer Nature Switzerland AG 2020

Abstract Purpose  This study aimed to assess the impact of overactive bladder on health-related quality of life (HRQoL) in a community-based sample of Korean population. Methods  The data of adults aged 19 and over that who participated in the 2012 Korean Community Health Survey were analyzed. Overactive bladder severity was classified as normal, mild, moderate, or severe using the Overactive Bladder Symptom scores, and HRQoL was evaluated using EQ-5D-3L. Relations between HRQoL and the severities and symptoms of OAB were investigated. Sampling weighted adjusted multiple regression analysis was performed to determine the effect of OAB symptom severity on HRQoL. Results  Of the 226,867 study subjects, 12,303 (5.4%) had OAB, and 552 (0.2%) had an OABSS of ≥ 12, indicating severe OAB. The problem -reporting rate significantly increased in all EQ-5D-3L dimensions as OAB severity increased. After adjusting for other variables, OAB severity had a significant effect on EQ-5D-3L index. Urge incontinence had greatest impact on quality of life. Conclusions  As the severity of OAB increased from mild to severe, quality of life decreased significantly. OAB was found to negatively affect HRQoL. Keywords  EQ-5D-3L · Health-related quality of life · Overactive bladder · Community HealthSurvey

Introduction Overactive bladder (OAB) is defined as urinary urgency and is usually accompanied by high frequency and nocturia with or without urge urinary incontinence, in the absence of a urinary tract infection or another obvious pathology [1]. The prevalence of OAB among adults varies by country and measurement method. However, it is estimated to be between 10 and 20% and tends to increase with advancing age [2–5]. Different symptoms within the OAB spectrum have significant effects on quality of life. Such symptoms can affect social, psychological, physical, and sexual health and work * Seon‑Ha Kim [email protected] 1



Department of Preventive Medicine, Dongguk University College of Medicine, Gyeongju‑si, Republic of Korea



Department of Nursing, Dankook University College of Nursing, 119 Dandae‑ro, Dongam‑gu, Cheonan, Chungnam 31116, Republic of Korea

2

productivity [4, 6–9]. Previous studies investigated the effect of OAB on health-related quality of life (HRQoL) using a variety of OAB classification criteria and HRQoL assessment tools. However, as the number of subjects was not sufficient, HRQoL comparisons were made according to some symptoms. There is a limit to comprehensively examining the effects of OAB on the HRQoL by severity and each symptom after adjusting for various covariates. HRQoL can be measured using general and diseasespecific tools. However, disease-specific tools may be susceptible to changes in the HRQoL of patients with specific diseases, but are difficult to compare with those