The Resolution of Inflammation

Much progress has been made in elucidating the mechanisms regulating the induction and progression of inflammatory diseases. More recently, however, it has become apparent that the manipulation of mechanisms governing the resolution of inflammation is an

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Series Editor Prof. Michael J. Parnham PhD Director of Preclinical Discovery Centre of Excellence in Macrolide Drug Discovery GlaxoSmithKline Research Centre Zagreb Ltd. Prilaz baruna Filipovic´a 29 HR-10000 Zagreb Croatia Advisory Board G. Z. Feuerstein (Wyeth Research, Collegeville, PA, USA) M. Pairet (Boehringer Ingelheim Pharma KG, Biberach a. d. Riss, Germany) W. van Eden (Universiteit Utrecht, Utrecht, The Netherlands)

Forthcoming titles: New Therapeutic Targets in Rheumatoid Arthritis, P.-P. Tak (Editor), 2008 Inflammatory Cardiomyopathy (DCM) – Pathogenesis and Therapy, H.-P. Schultheiß, M. Noutsias (Editors), 2008 Matrix Metalloproteinases in Tissue Remodelling and Inflammation, V. Lagente, E. Boichot (Editors), 2008 Angiogenesis in Inflammation: Mechanisms and Clinical Correlates, M.P. Seed, D.A. Walsh (Editors), 2008 Microarrays in Inflammation, A. Bosio, B. Gerstmayer (Editors), 2008 Bone Morphogenetic Proteins: From Local to Systemic Therapeutics, S. Vukicevic, K.T. Sampath (Editors), 2008 Natural Products for Joint Health, M.J.S. Miller (Editor), 2008 (Already published titles see last page.)

The Resolution of Inflammation

Adriano G. Rossi Deborah A. Sawatzky Editors

Birkhäuser Basel · Boston · Berlin

Editors Dr Adriano G. Rossi Dr Deborah A. Sawatzky MRC Centre for Inflammation Research Queen’s Medical Research Institute University of Edinburgh 47 Little France Crescent Edinburgh, EH16 4TJ Scotland United Kingdom

Library of Congress Control Number: 2007934182

Bibliographic information published by Die Deutsche Bibliothek Die Deutsche Bibliothek lists this publication in the Deutsche Nationalbibliografie; detailed bibliographic data is available in the internet at http://dnb.ddb.de

ISBN 978-3-7643-7505-8 Birkhäuser Verlag AG, Basel – Boston – Berlin The publisher and editor can give no guarantee for the information on drug dosage and administration contained in this publication. The respective user must check its accuracy by consulting other sources of reference in each individual case. The use of registered names, trademarks etc. in this publication, even if not identified as such, does not imply that they are exempt from the relevant protective laws and regulations or free for general use. This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, re-use of illustrations, recitation, broadcasting, reproduction on microfilms or in other ways, and storage in data banks. For any kind of use, permission of the copyright owner must be obtained. © 2008 Birkhäuser Verlag AG Basel · Boston · Berlin P.O. Box 133, CH-4010 Basel, Switzerland Part of Springer Science+Business Media Printed on acid-free paper produced from chlorine-free pulp. TCF ' Cover design: Markus Etterich, Basel Cover illustration: see page 126. With the friendly permission of Catherine Godson and Paola Maderna. Printed in Germany ISBN 978-3-7643-7505-8 e-ISBN 978-3-7643-7506-5 987654321

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