The Science and Practice of Lithium Therapy
This book provides a clear and comprehensive guide to the clinical prescription of lithium that draws upon evidence-based knowledge of its mechanisms of action. The book is divided into two parts, on the science of lithium and the practice of lithium ther
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Gin S. Malhi Marc Masson Frank Bellivier Editors
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The Science and Practice of Lithium Therapy
Gin S. Malhi • Marc Masson • Frank Bellivier Editors
The Science and Practice of Lithium Therapy
Editors Gin S. Malhi Professor and Chair Academic Department of Psychiatry Sydney Medical School The University of Sydney Sydney, Australia Marc Masson Medical Director Nightingale Hospitals Paris-Clinique du Château de Garches, Consultant Service Hospitalo-Universitaire Centre Hospitalier Sainte-Anne Paris, France
Frank Bellivier Professor, Assistance Publique – Hôpitaux de Paris INSERM UMR-S1144 Paris-Diderot University Paris, France Fondation FondaMental Creteil, France
ISBN 978-3-319-45921-9 ISBN 978-3-319-45923-3 DOI 10.1007/978-3-319-45923-3
(eBook)
Library of Congress Control Number: 2016959283 © Springer International Publishing Switzerland 2017 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper This Springer imprint is published by Springer Nature The registered company is Springer International Publishing AG The registered company address is Gewerbestrasse 11, 6330 Cham, Switzerland
Foreword
My lifelong love affair with lithium began 65 years ago, soon after graduating from the University of Sydney. I worked with some of the pioneers of lithium and, in particular, helped to make it a safer molecule to prescribe to patients. That initial wonder and excitement of a new treatment has never left me, and over the decades, I have seen countless people benefit from the effects of this seemingly magical element. The initial questions concerning efficacy and tolerability remain relevant today, and though much more is now known about the mechanisms of action of lithium, its precise effects and the reasons for its clinical specificity remain obscure. Lithium’s popularity has waxed and waned over the past half century. My own migration to North America allowed me to contribute to its introduction into clinical practice in the States in the 1970s. B
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