The Science of Reconstructive Transplantation
This volume presents a comprehensive overview of the latest advances in basic and translational research in the field of reconstructive transplantation and its potential therapeutic implications. Dr. Thomas E. Starzl and Dr. Raimund Margreiter, both pione
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Series Editor Kursad Turksen, Ph.D. [email protected]
Our understanding of stem cells has been growing rapidly over the last decade. While the apparently tremendous therapeutic potential of stem cells has not yet been realized, their routine use in regeneration and restoration of tissue and organ function is greatly anticipated. To this end, many investigators continue to push the boundaries in areas such as the reprogramming, the stem cell niche, nanotechnology, biomimetics and 3D bioprinting, to name just a few. To capture and consolidate some of these developments in a timely way is the objective of the volumes in this series. We want each volume to be thought-provoking in identifying problems, offering solutions and providing ideas to excite further innovation in the stem cell and regenerative medicine fields. More information about this series at http://www.springer.com/series/7896
Gerald Brandacher Editor
The Science of Reconstructive Transplantation Foreword by Dr. Thomas E. Starzl Foreword by Dr. Raimund Margreiter
Editor Gerald Brandacher Department of Plastic and Reconstructive Surgery The Johns Hopkins University School of Medicine Baltimore, MD, USA
ISSN 2196-8985 ISSN 2196-8993 (electronic) Stem Cell Biology and Regenerative Medicine ISBN 978-1-4939-2070-9 ISBN 978-1-4939-2071-6 (eBook) DOI 10.1007/978-1-4939-2071-6 Library of Congress Control Number: 2015930838 Springer New York Heidelberg Dordrecht London © Springer Science+Business Media New York 2015 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com)
For Barbara and Mo
Foreword: The Science of Reconstructive Transplantation
Reconstructive transplantation is an emerging area of transplant medicine that has become a viable option for patients with large and devastating tissue defects. Over the past decade, a rapidly growing number of face and upper extremity transplantations have been performed
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