The So Called Pre-Neoplastic Lesions and Carcinoma In Situ
In situ breast cancer represents 15 % to 30 % of all diagnosed cancer, from all the in situ breast cancer 80 % of them are ductal carcinoma or DCIS [1, 2]. Similar to invasive breast cancer, DCIS is not a single disease but rather many different diseases,
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The Pathobiology of Breast Cancer
The Pathobiology of Breast Cancer
Jose Russo
The Pathobiology of Breast Cancer
Jose Russo Fox Chase Cancer Center Philadelphia, PA, USA
ISBN 978-3-319-40813-2 ISBN 978-3-319-40815-6 DOI 10.1007/978-3-319-40815-6
(eBook)
Library of Congress Control Number: 2016945167 © Springer International Publishing Switzerland 2016 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper This Springer imprint is published by Springer Nature The registered company is Springer International Publishing AG Switzerland
Contents
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The Windows of Susceptibility to Breast Cancer ................................. 1.1 Introduction ...................................................................................... 1.2 Risk Factor and Etiological Agents.................................................. 1.3 The Concept of the Windows of Susceptibility to Carcinogenesis ............................................................................... 1.4 The Windows of Susceptibility Apply to Human Breast Cancer ..... 1.5 Effect of Hormones on Breast Cancer ............................................. 1.6 Hormones as Carcinogens................................................................ 1.7 Role of Breast Development and Cancer ......................................... 1.8 Fertility and Breast Cancer Risk ...................................................... 1.9 Conclusions ...................................................................................... References .................................................................................................
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The So Called Pre-Neoplastic Lesions and Carcinoma In Situ .......... 2.1 Introduction ...................................................................................... 2.2 The So Called Pre-neoplastic Lesions ............................................. 2.2.1 Ductal Hyperplasia..........................................................
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