The Toxicity of (Nano)Microplastics on C. elegans and Its Mechanisms

Microplastics (MPs) and nanoplastics (NPs) are respectively defined as plastic debris with sizes of

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Contents 1 Introduction 1.1 Nanoplastics 1.2 Toxicology of Nanoplastics 1.3 Caenorhabditis elegans 2 Toxicities of (Nano)Microplastics in C. elegans 2.1 Developmental and Reproductive Toxicity 2.2 Behavioral and Neural Toxicity 2.3 Intestine Damages 2.4 Oxidative Stress 3 Mechanisms of (Nano)Microplastics’ Toxicities in C. elegans 3.1 The Insulin Signaling Pathway 3.2 The Protective Response Mediated by the Intestinal p38 Signaling 3.3 Other Mechanisms 4 Summary References

Abstract Microplastics (MPs) and nanoplastics (NPs) are respectively defined as plastic debris with sizes of