Toxoplasma gondii
For years, toxoplasmosis has been known as disease mostly affecting newborns. Since immunocompromised patients (AIDS) present a high risk of reactivation of chronic toxoplasmosis this parasitic disease has gained increasing interest. Besides presenting cl
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Editors R.W Compans, Atlanta/Georgia M. Cooper, Birmingham/Alabama . H. Koprowski, Philadelphia/Pennsylvania . F. Melchers, Basel M. Oldstone, La Jolla/California . S. Olsnes, Oslo M. Potter, Bethesda/Maryland . H. Saedler, Cologne P K. Vogt, La Jolla/California . H. Wagner, Munich
Springer-Verlag Berlin Heidelberg GmbH
Toxoplasma gondii Edited by U. Gross
With 31 Figures and 14 Tables
Springer
PO OR. UWE GROSS Institute for Hygiene and Microbiology University of Wurzburg Josef-Schneider-Str. 2 0-97080 Wurzburg Germany
Cover illustration: Immunolocalization of the bradyzoite-specific antigen BAGI within tissue cysts of Toxoplasma gondii. Top picture shows a light microscopic image of a peroxidase-stained cyst within the brain of a chronical/y infected mouse. Left insert: a confocallaserscan of a fluorescence-Iabeled cell culturederived cyst presenting the positively stained bradyzoites (orange) within the cyst while the surrounding tachyzoites are negative (green). Right insert: electron micrograph of the periphery of a tissue cyst showing the gold particles (pseudocolored) over the cytoplasm of the bradyzoites. Cover illustration provided by DJ.P Ferguson and U Gross Cover design: Springer-Verlag Heidelberg, Design & Production
ISBN 978-3-642-51016-8 ISBN 978-3-642-51014-4 (eBook) DOI 10.1007/978-3-642-51014-4 This work is subiect to copyright. AII rights are reserved, whether the whole or part 01 the material is concerned, specilically the rights 01 translation, reprinting, reuse 01 illustrations, recitation, broadcasting, reproduction on microlilms or in any other way, and storage in data banks. Ouplication 01 this publication or parts thereol is permitted only under the provisions 01 the German Copyright Law 01 September 9, 1965, in its current version, and permission lor use must always be obtained lrom Springer-Verlag. Violations are liable for prosecution under the German Copyright Law. © Springer-Verlag Berlin Heidelberg 1996 Originally published by Springer-Verlag Berlin Heidelberg New York in 1996 Softcover reprint of the hardcover 1st edition 1996
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Preface
Toxop/asma gondii has been recognized as one of the most successful protozoan parasites infecting 10%-25% of the world's human population. For a long time, toxoplasmosis has been known as a disease severely affecting newborns who have acquired the parasite in utero. Post-natally acquired toxoplasmosis is usually an asymptomatic inf
