Translating Molecules into Medicines Cross-Functional Integration at
Tackling translational medicine with a focus on the drug discovery development-interface, this book integrates approaches and tactics from multiple disciplines, rather than just the pharmaceutical aspect of the field. The authors of each chapter address t
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Shobha N. Bhattachar John S. Morrison · Daniel R. Mudra David M. Bender Editors
Translating Molecules into Medicines Cross-Functional Integration at the Drug DiscoveryDevelopment Interface
AAPS Advances in the Pharmaceutical Sciences Series The AAPS Advances in the Pharmaceutical Sciences Series, published in partnership with the American Association of Pharmaceutical Scientists, is designed to deliver volumes authored by opinion leaders and authorities from around the globe, addressing innovations in drug research and development, and best practice for scientists and industry professionals in the pharma and biotech industries.
Volume 25 Series Editors Daan J.A. Crommelin Robert A. Lipper
More information about this series at http://www.springer.com/series/8825
Shobha N. Bhattachar • John S. Morrison Daniel R. Mudra • David M. Bender Editors
Translating Molecules into Medicines Cross-Functional Integration at the Drug Discovery-Development Interface
Editors Shobha N. Bhattachar Small Molecule Design and Development Eli Lilly and Company Indianapolis, IN, USA Daniel R. Mudra ADME, Drug Disposition Eli Lilly and Company Indianapolis, IN, USA
John S. Morrison Pharmaceutical Candidate Optimization Bristol-Myers Squibb Wallingford, CT, USA David M. Bender Small Molecule Design and Development Eli Lilly and Company Indianapolis, IN, USA
ISSN 2210-7371 ISSN 2210-738X (electronic) AAPS Advances in the Pharmaceutical Sciences Series ISBN 978-3-319-50040-9 ISBN 978-3-319-50042-3 (eBook) DOI 10.1007/978-3-319-50042-3 Library of Congress Control Number: 2017937715 © American Association of Pharmaceutical Scientists 2017 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Printed on acid-free paper This Springer imprint is published by Springer Nature The registered company is Springer International Publishing AG The registered company address is: Gewerbestrasse 11
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