Tutorials in Mathematical Biosciences II Mathematical Modeling of Ca
This book presents a series of models in the general area of cell physiology and signal transduction, with particular attention being paid to intracellular calcium dynamics, and the role played by calcium in a variety of cell types. Calcium plays a crucia
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James Sneyd (Ed.)
Tutorials in Mathematical Biosciences II Mathematical Modeling of Calcium Dynamics and Signal Transduction
With Contributions by: R. Bertram · J.L. Greenstein · R. Hinch E. Pate · J. Reisert · M.J. Sanderson T.R. Shannon · J. Sneyd · R.L. Wilson
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Editor
James Sneyd Department of Mathematics University of Auckland Private Bag 92019 Auckland 1020, New Zealand E-mail: [email protected]
Cover Figure: Calcium signalling: dynamics, homeostasis and remodeling c 2003 Nature Publishing Group
Library of Congress Control Number: 2004109594 Mathematics Subject Classification (2000): 92C37, 92C30, 92C05 ISSN print edition: 0075-8434 ISSN electronic edition: 1617-9692 ISBN-10 3-540-25439-0 Springer Berlin Heidelberg New York ISBN-13 978-3-540-25439-6 Springer Berlin Heidelberg New York DOI 10.1007/b107088 This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilm or in any other way, and storage in data banks. Duplication of this publication or parts thereof is permitted only under the provisions of the German Copyright Law of September 9, 1965, in its current version, and permission for use must always be obtained from Springer. Violations are liable for prosecution under the German Copyright Law. Springer is a part of Springer Science+Business Media springeronline.com c Springer-Verlag Berlin Heidelberg 2005 Printed in The Netherlands The use of general descriptive names, registered names, trademarks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. Typesetting by the authors and Techbooks using a Springer LATEX package Cover design: design & produktion GmbH, Heidelberg Printed on acid-free paper
SPIN: 11406501
41/Techbooks
543210
Preface
This is the second volume in the series “Lectures in Mathematical Biosciences”. These lectures are based on material which was presented in tutorials or developed by visitors and postdoctoral fellows of the Mathematical Bioscience Institute (MBI), at The Ohio State University. The aim of this series is to introduce graduate students and researchers with just a little background in either mathematics or biology to mathematical modeling of biological processes. The present volume is devoted to Mathematical Modeling of Calcium Dynamics and Signal Transduction, which was the focus of the MBI program in the winter of 2004; documentation of that program, including streaming videos of the workshops, can be found on the website http://mbi.osu.edu. This volume was organized and edited by James Sneyd. Sneyd is a world leader in mathematical physiology and biology, and has been working extensively on modeling biological processes of signal transduction induced by calcium oscillations. Some of the chapters describe mathema
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