Uptake and Trafficking of Protein Toxins
This volume focuses on the transport of medically relevant bacterial protein toxins into mammalian cells, and on novel pharmacological strategies to inhibit toxin uptake. The first chapters review our current understanding of the cell-surface receptors an
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Holger Barth Editor
Uptake and Trafficking of Protein Toxins
Current Topics in Microbiology and Immunology Volume 406
Series editors Rafi Ahmed School of Medicine, Rollins Research Center, Emory University, Room G211, 1510 Clifton Road, Atlanta, GA 30322, USA Klaus Aktories Medizinische Fakultät, Institut für Experimentelle und Klinische Pharmakologie und Toxikologie, Abt. I, Albert-Ludwigs-Universität Freiburg, Albertstr. 25, 79104, Freiburg, Germany Arturo Casadevall W. Harry Feinstone Department of Molecular Microbiology & Immunology, Johns Hopkins Bloomberg School of Public Health, 615 N. Wolfe Street, Room E5132, Baltimore, MD 21205, USA Richard W. Compans Department of Microbiology and Immunology, Emory University, 1518 Clifton Road, CNR 5005, Atlanta, GA 30322, USA Jorge E. Galan Boyer Ctr. for Molecular Medicine, School of Medicine, Yale University, 295 Congress Avenue, room 343, New Haven, CT 06536-0812, USA Adolfo García-Sastre Icahn School of Medicine at Mount Sinai, Department of Microbiology, 1468 Madison Ave., Box 1124, New York, NY 10029, USA Tasuku Honjo Faculty of Medicine, Department of Medical Chemistry, Kyoto University, Sakyo-ku, Yoshida,, Kyoto 606-8501, Japan Bernard Malissen Centre d’Immunologie de Marseille-Luminy, Parc Scientifique de Luminy, Case 906, 13288, Marseille Cedex 9, France Klaus Palme Institute of Biology II/Molecular Plant Physiology, Albert-Ludwigs-Universität Freiburg, Freiburg, 79104, Germany Rino Rappuoli GSK Vaccines, Via Fiorentina 1, Siena, 53100, Italy
Honorary Editor Michael B. A. Oldstone Department of Immunology and Microbiology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA Peter K. Vogt Department of Molecular and Experimental Medicine, The Scripps Research Institute, 10550 North Torrey Pines Road, BCC-239, La Jolla, CA 92037, USA
More information about this series at http://www.springer.com/series/82
Holger Barth Editor
Uptake and Trafficking of Protein Toxins Responsible series editor: Klaus Aktories
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Editor Holger Barth Institute of Pharmacology and Toxicology University of Ulm Medical Center Ulm Germany
ISSN 0070-217X ISSN 2196-9965 (electronic) Current Topics in Microbiology and Immunology ISBN 978-3-319-58891-9 ISBN 978-3-319-58893-3 (eBook) DOI 10.1007/978-3-319-58893-3 Library of Congress Control Number: 2017955822 © Springer International Publishing AG 2017 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt
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