Validation of echocardiographic indices of right ventriclular systolic function with cardiac magnetic resonance: a compa
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Validation of echocardiographic indices of right ventriclular systolic function with cardiac magnetic resonance: a comparative study Suchi K Grover1*, Darryl P Leong1, Payman Molaee2, Mitra Shirazi2, Adhiraj Chakrabarty1, Amy Penhall1, Rebecca Perry1, Majo Joseph1, Joseph B Selvanayagam1 From 2011 SCMR/Euro CMR Joint Scientific Sessions Nice, France. 3-6 February 2011 Introduction Right ventricular ejection fraction (RVEF) is an important predictor of outcome in heart failure patients. Although cardiac magnetic resonance (CMR) assessment of RV function is considered gold standard and echocardiographic measurement of RVEF is challenging due to its unique geometry; CMR still has limited availability in the wider community. Therefore alternative echocardiographic indices such as tricuspid annular plane systolic excursion (TAPSE), peak tricuspid annular systolic velocity (RV S’) and RV fractional area change (RV FAC) have been evaluated and demonstrated prognostic value, however, comparison studies with RVEF by CMR are limited. Purpose Our objective was to evaluate echocardiographic indices of RV function such as TAPSE, RV S’, and RV FAC and compare these with CMR assessment of RVEF and patient functional status. Methods We prospectively recruited 73 subjects: 56 with newly diagnosed systolic heart failure (age 55±27 years) and 17 healthy controls (age 53±8 years). Subjects underwent transthoracic echocardiography, CMR, both under similar loading conditions; and 6-minute walk test. Echocardiographic E and A velocities, TAPSE, RV S’ and RV areas were measured in the conventional manner. Ventricular volumes were measured from cine CMR images by planimetry. 1 Flinders Medical Centre, Bedford Park, Australia Full list of author information is available at the end of the article
Results TAPSE exhibited the strongest correlation with CMR RVEF (r2 = 0.42, p
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