Validation of population-based cut-offs for low muscle mass and strength

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EDITORIAL

Validation of population‑based cut‑offs for low muscle mass and strength Pinar Soysal1 · Lee Smith2 · Ahmet Turan Isik3

© European Geriatric Medicine Society 2020

Keywords  Muscle mass · Muscle strength · Cut-off With prolonged life expectancy, existing comorbid diseases have become insufficient to evaluate the health status of older adults. The conceptual occurrence of geriatric syndromes specific to old age has now emerged [1]. Although dementia, incontinence, polypharmacy, falls, malnutrition have been studied for many years, some geriatric syndromes have only been discussed over the past few decades [1]. One example is sarcopenia, characterized by progressive muscle strength and decrease in mass, which eventually results in functional decline, physical disabilities, falls, fractures, poor quality of life, frequent hospitalizations and mortality. Thus early diagnosis is critical to prevent these adverse outcomes [2]. Since it is a new geriatric syndrome, the definition and criteria of sarcopenia have changed recently [3]. In 2010, The European Working Group on Sarcopenia in Older People (EWGSOP) suggested that the presence of both low muscle mass (MM) and low muscle function (strength or performance) for its diagnosis [4]. However, these guidelines were revised in 2019 by the EWGSOP2, wherein muscle strength (MS) was considered as strength and is a better predictor of adverse outcomes than MM [3]. Moreover, the uncertainty in diagnosis is not limited to whether MM or MS should be prioritized in the algorithm. Gender and ethnic differences have forced different geographical regions to determine their

own cut-off values for sarcopenia. In a study published in the last issue of the European Geriatric Medicine Journal, it was aimed to determine cut-offs for low MS and low MM and find out the prevalence of sarcopenia in Indians [5]. The study by Pal et al. found that handgrip strength