Validation of the Lebanese Medication Adherence Scale among Lebanese diabetic patients
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RESEARCH ARTICLE
Validation of the Lebanese Medication Adherence Scale among Lebanese diabetic patients Liliane Ibrahim1 · Lina Ibrahim1 · Souheil Hallit2,3 · Pascale Salameh2,4,5 · Hala Sacre2 · Marwan Akel2,6 · Rola Bou Serhal1,7,8 · Nadine Saleh1,5 Received: 9 March 2020 / Accepted: 4 November 2020 © Springer Nature Switzerland AG 2020
Abstract Background Adherence to oral antidiabetics plays a pivotal role in controlling diabetes. Healthcare workers evaluate this adherence when visited by patients. Objectives The primary objective of this study was to validate the existing LMAS-14 (Lebanese Medication Adherence Scale) in Lebanese diabetic adults. The secondary objective was to evaluate factors affecting adherence among this population. Setting The main five Lebanese governorates. Methods This study was conducted between May and September 2019, and community dwelling adult participants were enrolled using a proportionate random sample. The scale was validated using factor analysis and reliability testing, while bivariate and multivariable analyses assessed correlates of adherence. Main outcomes measures Validity of LMAS-14. Results A total of 308 participants were included, and the response rate was 91.25%. All LMAS-14 items converged over a solution of four factors, explaining a total of 64.39% of the variance (α = 0.859). The cutoff point between controlled and uncontrolled patients was set at 11. The sensitivity and specificity were good at this cutoff (71.1% and 94.74%, respectively). Results showed that 167 (57.2%) patients had good medication adherence. Advanced age (Beta = 0.046; p = 0.001) and having medical coverage (Beta = 1.452; p = 0.005) were significantly associated with higher adherence. Furthermore, adherence to oral antidiabetic drugs (Beta = 1.197; p = 0.018), female gender (Beta = 2.695; p = 0.011), and taking dyslipidemia medication (Beta = 3.527; p = 0.005) predicted higher diabetes control. Conclusion This study validated the LMAS among Lebanese adult diabetic patients taking oral antidiabetic drug. Advanced age and having medical coverage were associated with higher medication adherence. Further national studies are warranted to corroborate our findings. Keywords Diabetes · Lebanon · LMAS-14 · Medication adherence · Oral antidiabetic Abbreviations LMAS Lebanese Medication Adherence Scale OAD Oral antidiabetic drugs WHO World Health Organization DMAS Diabetes Medication Adherence Scale PPV Positive predictive
NPV Value negative predictive value PAI Physical Activity Index ADA American Diabetes Association
First co-authors: Liliane Ibrahim and Lina Ibrahim. * Liliane Ibrahim [email protected] 1
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Faculty of Pharmacy, Lebanese University, Beirut, Lebanon
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School of Pharmacy, Lebanese International University, Beirut, Lebanon
Department of Epidemiology and Biostatistics, Faculty of Public Health, Lebanese University, Fanar, Lebanon
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INSPECT‑LB, National Institute of Public Health, Clinical Epidemiology and Toxicology-Liban, Beirut, Lebanon
Clin
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