Variations in clinical features and oncologic behaviors of T1 colorectal cancer according to tumor location

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ORIGINAL ARTICLE

Variations in clinical features and oncologic behaviors of T1 colorectal cancer according to tumor location Akira Ouchi1 · Kazuhiro Toriyama2 · Takashi Kinoshita1 · Tsutomu Tanaka3 · Yasuhiro Shimizu1 · Yasumasa Niwa3 · Masahiro Tajika3 · Koji Komori1 Received: 28 November 2019 / Accepted: 20 February 2020 © Japan Society of Clinical Oncology 2020

Abstract Background  Different genetic characteristics according to tumor location result in variations in survival rates and treatment responses in advanced colorectal cancer (CRC). However, the effects of tumor location during early CRC are still unclear. Methods  Patients with T1 CRC treated between 2003 and 2019 were enrolled from a prospectively collected database. Patients were once divided into four groups, then combined into two groups (right- and left-sided CRC) according to the tumor location, and clinical features and oncologic behaviors were compared. Results  In total, 458 patients were analyzed. Right-sided CRC had a lower incidence of polypoid type tumor than left-sided CRC (36/126 (28.6%) vs 186/332 (56.0%), p 

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