Vascular screening in asymptomatic subjects using non-contrast MRA
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POSTER PRESENTATION
Open Access
Vascular screening in asymptomatic subjects using non-contrast MRA Yuki Sekine-Ohmoto1*, Makiko Ishihara2, Takashi Yoshida3, Junji Takahashi3, Takashi Yamamoto1, Hiroyuki Tsuji1, Yasuji Arase1 From 15th Annual SCMR Scientific Sessions Orlando, FL, USA. 2-5 February 2012 Summary Vascular screening including the coronary, carotid, renal arteries and aorta using non-contrast MRA in 300 asymptomatic subjects detected atherosclerosis lesions including the coronary artery in 5% of participants. Background Atherosclerosis is a systemic disease affecting arteries in a whole body and a major cause of death in the world. There are few data, however, on the extent of the diseases associated with atherosclerosis in asymptomatic subjects. Objective of this study was to identify the prevalence of cardiovascular diseases in asymptomatic subjects using non-contrast MRA. Methods We performed vascular screening including the coronary, carotid, renal arteries and aorta using MRA (1.5 T commercial scanner, Toshiba Medical Systems Excelart Vantage TM powered by Atlas) and biochemistry tests in asymptomatic subjects from October 2008 to July 2011. Imaging of carotid arteries was performed by time of flight methods. Imaging of coronary arteries was performed by corrected respiratory-triggered and cardiactriggered steady-state-free-precision (SSFP) sequence with fat suppression and T2 preparation. The data of the magnetic resonance coronary angiography (MRCA) was transferred to the workstation with image reconstruction software (AZE VirtualPlace Fujin, AZE Ltd., Tokyo, Japan). Imaging of renal arteries was performed by steady-state-free-precision (SSFP) sequence with time-SLIP pulse. The diseases of the aorta were detected
by sagittal images of the coronary artery and coronal images of the renal artery by which the whole aorta from the ascending aorta to common iliac arteries was covered.
Results There were 186 males and 114 females with a mean age of 59±10 and 64±9, respectively. Six subjects (2%) had coronary diseases, (occluded in two, severe stenosis in four) six (2%) had carotid artery diseases (internal carotid artery occluded in two, moderate stenosis in four), two (0.7%) had renal artery disease, two had aortic disease (thoracic aortic aneurysm), and two had peripheral artery (common ileac artery) aneurysms. Two had atherosclerotic diseases in 2 lesions simultaneously. Thoracic aortic aneurysm was detected by sagittal images of MRCA, and common iliac artery aneurysm by coronal images of the renal artery. Conclusions Asymptomatic atherosclerosis lesions including the coronary artery were detected by non-contrast MRA in 5% of participants. Non-contrast MRA is a useful and noninvasive technique without radiation exposure for vascular screening. Funding None. Author details 1 Health Management Center, Toranomon Hospital, Tokyo, Japan. 2Imaging Center, Toranomon Hospital, Tokyo, Japan. 3Radiology, Toranomon Hospital, Tokyo, Japan. Published: 1 February 2012
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Health Management Center, Toranomon Hos
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