What we know about 2019-nCoV in Iran in the early stage?

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What we know about 2019-nCoV in Iran in the early stage? Milad Dodangeh1 • Masoud Dodangeh2 • Mohammadamin Joulani1 Azinmehr Elahian Boroujeni1



Received: 13 March 2020 / Accepted: 28 April 2020 Ó Indian Virological Society 2020

Abstract On 10 January 2020, a new coronavirus causing a pneumonia outbreak spread rapidly in all of the World. On 19 February 2020, the first official announcement of death from 2019-Nov was made in Iran. As of 7 March 2020, there were 101,927 confirmed cases of Covid-19 infection, including 3486 deaths, reported in the World. In the eastern and Mediterranean region Iran with 4747 confirmed cases of Covid-19 infection and 124 deaths, is in the critical stage. Therefore, there is a matter of urgency combating this new virus and stopping the epidemic. Here, we focus on symptoms and the development of fast diagnosis methods, as well as potential management to prevent or treat the Covid-19 infection. Keywords Coronavirus  Covid-19  2019-nCov  Iran

Introduction One of the major causes of morbidity and mortality worldwide is viruses [4, 7]. Coronaviruses (CoVs) belong to the family Coronaviridae in the order Nidovirales and they are enveloped, positive-sense, single-stranded RNA viruses. They have the zoonotic origin and they are distributed broadly among humans and other animals like mammals and birds, which cause respiratory, hepatic, enteric, and neurologic diseases [13]. Two fatal & Milad Dodangeh [email protected]; [email protected] 1

Student Research Committee (SRC), Faculty of Medicine, Iran University of Medical Sciences (IUMS), Shahid Hemmat Highway, Tehran 1449614535, Iran

2

Tehran, Iran

coronaviruses emerged periodically in the world in 2002 and 2012. The first one was severe acute respiratory syndrome coronavirus (SARSCoV) and the second one was Middle East respiratory syndrome coronavirus (MERSCoV) [12].On 10 January 2020, the World Health Organization (WHO) identified the unknown pathogen as a novel coronavirus denoted as Covid-19 or 2019-nCoV. On 19 February the first case was reported in Iran [14]. The patient was found in the Kamkar-Arabnia Hospital of Qom, a city located near Tehran [2]. Currently, Tehran, Qom, and Mazandaran have the highest number of patients in Iran and are in critical condition. However, no city has been quarantined in Iran and this has led to an increasing number of patients every day. As of 7 March 2020, there were 101,927 confirmed cases of Covid-19 infection, including 3486 deaths, reported in all of the world. In the eastern and Mediterranean region, Iran with 4747 confirmed cases of Covid-19 infection and 124 deaths, is in the critical stage [15].

How did Covid-19 start in Iran? Iranian authorities have put forward two theories for the start of the 2019-nCoV in Iran. The first theory was an Iranian airline flying many times to China at the Wuhan 2019-nCoV outbreak. The second theory was the return of an Iranian businessman who had returned from china to Qom with several flights [2]. Neither of these two theories has