156 Pulmonary vein imaging by 3D non-contrast, free breathing SSFP MR angiography; a novel technique
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BioMed Central
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Meeting abstract
156 Pulmonary vein imaging by 3D non-contrast, free breathing SSFP MR angiography; a novel technique Aparna Singhal*1, Anderanik Tomasian1, Alex Sassani1, Vibhas Deshpande2, Gerhard Laub1, J Paul Finn1, Stefan Ruehm1 and Mayil S Krishnam1 Address: 1UCLA, Los Angeles, CA, USA and 2Siemens Medical Solutions, Los Angeles, CA, USA * Corresponding author
from 11th Annual SCMR Scientific Sessions Los Angeles, CA, USA. 1–3 February 2008 Published: 22 October 2008 Journal of Cardiovascular Magnetic Resonance 2008, 10(Suppl 1):A57
doi:10.1186/1532-429X-10-S1-A57
Abstracts of the 11th Annual SCMR Scientific Sessions - 2008
Meeting abstracts – A single PDF containing all abstracts in this Supplement is available here. http://www.biomedcentral.com/content/pdf/1532-429X-10-S1-info.pdfThis abstract is available from: http://jcmr-online.com/content/10/S1/A57 © 2008 Singhal et al; licensee BioMed Central Ltd.
Introduction
Methods
Radiofrequency ablation of foci in pulmonary veins has emerged as a therapeutic option for patients with medically refractory atrial fibrillation or those unable to tolerate drugs. Preprocedural imaging is important and is being increasingly utilized to assess pulmonary venous anatomy. Contrast enhanced Magnetic Resonance Angiography (CEMRA) has been shown to be an efficient modality for assessment of pulmonary veins with excellent spatial resolution without any exposure to radiation and iodinated contrast. However, CE-MRA is operator dependant and requires patient cooperation for breath holding. Additionally, high dose gadolinium use has been recently reported to be associated with the occurrence of Nephrogenic Systemic Fibrosis (NSF) in certain patients including renal disease patients. Recently, three dimensional navigator gated free breathing selective steady-state free precession (SSFP) sequence has been employed to display non-contrast MR angiography of the heart and great vessels. The SSFP causes inherent high contrast between the blood pool and background tissues in the body due to high T2/T1 ratio.
Twenty consecutive patients (age range 30–81) with known atrial fibrillation underwent free-breathing ECGgated non-contrast SSFP MRA with non-selective radiofrequency excitation and conventional high-resolution 3D CEMRA of thorax at 1.5 T. Two readers evaluated both datasets for vein definition (from 0, not visualized to 3, excellent definition), artifacts, findings, and intra-vascular signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) in the pulmonary veins. Pulmonary vein ostial measurements were also made in both the datasets. Statistical analysis was performed using Wilcoxon test, paired ttest, and kappa co-efficient.
Purpose To investigate the feasibility of non-contrast 3D SSFP MR Angiography for evaluation of pulmonary veins and to correlate the results with conventional contrast-enhanced MRA (CE-MRA).
Results Reader 1 and 2 graded 85 (96.6%) and 81(92.1%) segments on SSFP MRA, and 84 (100%) and 84 (100%) segments on C
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