2117 High-resolution 3D free-breathing coronary MR angiography using wideband SSFP at 3 Tesla
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Meeting abstract
2117 High-resolution 3D free-breathing coronary MR angiography using wideband SSFP at 3 Tesla Hsu-Lei Lee*1, Ajit Shankaranarayanan2, Gerald M Pohost3 and Krishna S Nayak1 Address: 1Department of Electrical Engineering, University of Southern California, Los Angeles, CA, USA, 2Global Applied Science Lab, GE Healthcare, Waukesha, WI, USA and 3Division of Cardiovascular Medicine, University of Southern California, Los Angeles, CA, USA * Corresponding author
from 11th Annual SCMR Scientific Sessions Los Angeles, CA, USA. 1–3 February 2008 Published: 22 October 2008 Journal of Cardiovascular Magnetic Resonance 2008, 10(Suppl 1):A386
doi:10.1186/1532-429X-10-S1-A386
Abstracts of the 11th Annual SCMR Scientific Sessions - 2008
Meeting abstracts – A single PDF containing all abstracts in this Supplement is available here. http://www.biomedcentral.com/content/pdf/1532-429X-10-S1-info.pdfThis abstract is available from: http://jcmr-online.com/content/10/S1/A386 © 2008 Lee et al; licensee BioMed Central Ltd.
Introduction Steady-state free precession (SSFP) imaging at 3 T can be used to generate coronary artery images with substantially higher signal to noise ratio (SNR) and blood-myocardium contrast to noise ratio (CNR) compared to 1.5 T, but is limited by potentially severe off-resonance artifacts [1]. The need for a short TR (to avoid banding) limits the spatial resolution to > 1 mm using conventional gradients, making it difficult to achieve the sub-millimeter resolution needed for accurately evaluating coronary artery stenoses.
Wideband SSFP uses two alternating repetition times to increase the band spacing in the steady-state frequency response, with a modest sacrifice in SNR [2]. It can suppress off-resonance related artifacts in cardiac imaging for a given spatial resolution. We demonstrate the application of wideband SSFP to 3D free-breathing coronary artery imaging at 3 T, and compare results with conventional SSFP at 3 T.
Methods Experiments were performed on a Signa Excite HD 3 T scanner (GE Healthcare, Waukesha, WI) with gradients capable of 40 mT/m amplitude and 150 mT/m/ms slew
Figure 1
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Journal of Cardiovascular Magnetic Resonance 2008, 10(Suppl 1):A386
http://jcmr-online.com/content/10/S1/A386
Figure We demonstrate 2 sub-millimeter resolution 3D SSFP coronary artery imaging at 3 Tesla using the wideband SSFP technique We demonstrate sub-millimeter resolution 3D SSFP coronary artery imaging at 3 Tesla using the wideband SSFP technique. Images of the LMCA and proximal LAD were obtained with 0.68 × 1.0 × 1.0 mm resolution and without the banding artifacts experienced by conventional SSFP.
rate, using an 8-channel phased-array cardiac coil. Three healthy volunteers were scanned after providing informed consent. Navigator-gated sequences, illustrated in Figure 1, were used to image the LMCA and proximal LAD in mid-diastole. A conventional cylindrical navigator (4.3 ms excitation), is followed b
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