18 F-FDG PET/CT is Useful for Pretreatment Assessment of the Histopathologic Type of Thymic Epithelial Tumors
- PDF / 408,095 Bytes
- 8 Pages / 595.276 x 790.866 pts Page_size
- 50 Downloads / 154 Views
ORIGINAL ARTICLE
18
F-FDG PET/CT is Useful for Pretreatment Assessment of the Histopathologic Type of Thymic Epithelial Tumors
Ji Young Kim & Hye Ok Kim & Jae Seung Kim & Dae Hyuk Moon & Yong Hee Kim & Dong Kwan Kim & Seung-II Park & Young Soo Park & Jin-Sook Ryu
Received: 24 February 2010 / Revised: 10 May 2010 / Accepted: 14 May 2010 / Published online: 9 June 2010 # Korean Society of Nuclear Medicine 2010
Abstract Purpose This study was performed to assess the usefulness of 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography (PET) or PET/computed tomography (CT) for distinguishing thymic epithelial tumors according to World Health Organization (WHO) classifications. Methods We analyzed a total of 45 patients (range, 29– 75 years of age; mean, 55 years) with pathologically confirmed thymic epithelial tumors who underwent pretreatment 18F-FDG PET or PET/CT between November 2003 and October 2009. The size, visual grading of uptake value, peak standardized uptake value (SUVpeak), uptake pattern, and contour of each tumor, and associated findings on PET or PET/CT, were analyzed relative to the three simplified WHO subgroups: less-invasive thymomas (types A and AB), more-invasive thymomas (types B1, B2, and B3) and thymic carcinomas. We statistically assessed the relationship of 18F-FDG PET or PET/CT findings with these simplified subgroups. Results Of the 45 patients, ten had less-invasive thymomas, 23 had more-invasive thymomas, and 12 had thymic J. Y. Kim : H. O. Kim : J. S. Kim : D. H. Moon : J.-S. Ryu (*) Department of Nuclear Medicine, Asan Medical Center, University of Ulsan College of Medicine, 86 Asanbyeonwon-gil, Pungnap-dong, Songpa-gu, Seoul 138-736, Korea e-mail: [email protected] Y. H. Kim : D. K. Kim : S.-I. Park Department of Thoracic Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea Y. S. Park Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
carcinomas. The SUVpeak of the less- and more-invasive thymomas were significantly lower than those of thymic carcinomas (p
Data Loading...
