A Primer of Neuroimmunological Disease
A Primer of Neuroimmunological Disease is a significant new resource for anyone interested in conditions such as multiple sclerosis(MS), myasthenia gravis, and neurological infections. It is a practical and balanced guide to the diagnosis and t
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Andrew R. Pachner
A Primer of Neuroimmunological Disease
Andrew R. Pachner Department of Neurology and Neuroscience New Jersey Medical School University of Medicine and Dentistry of New Jersey Newark, NJ, USA
ISBN 978-1-4614-2187-0 e-ISBN 978-1-4614-2188-7 DOI 10.1007/978-1-4614-2188-7 Springer New York Dordrecht Heidelberg London Library of Congress Control Number: 2012930829 © Springer Science+Business Media, LLC 2012 All rights reserved. This work may not be translated or copied in whole or in part without the written permission of the publisher (Springer Science+Business Media, LLC, 233 Spring Street, New York, NY 10013, USA), except for brief excerpts in connection with reviews or scholarly analysis. Use in connection with any form of information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed is forbidden. The use in this publication of trade names, trademarks, service marks, and similar terms, even if they are not identified as such, is not to be taken as an expression of opinion as to whether or not they are subject to proprietary rights. While the advice and information in this book are believed to be true and accurate at the date of going to press, neither the authors nor the editors nor the publisher can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the material contained herein. Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com)
Preface
Neuroimmunologists deal with the nervous system and the immune system, both of which are giant, complex communication networks. One would think that we would be excellent communicators ourselves, but we have not communicated well with individuals outside our field. This is very unfortunate because the field of neuroimmunology is more dependent than most on input from fields outside its own. Researchers in basic neuroscience, basic immunology, clinical neurology (to name just a few) have much to contribute and these contributions would be enhanced if those researchers had a better understanding of neuroimmunology. This book is an attempt to provide a basic understanding of some of the neuroimmunological diseases to individuals who are not neuroimmunologists. Who should use this book? I have lofty ambitions for this book in that I think it can be helpful to a large number of people, such as basic scientists in both neuroscience and immunology, neurologists, and motivated individuals in pharmaceutical companies who are neither PhDs nor MDs. Like Icarus, who had to navigate a path not too close to the sun nor too close to the sea, I tried to be basic enough to be understood by neophytes yet having enough depth so that it would not lose the attention of more-educated readers. Time will tell whether I succeeded. Why now? There are many reasons. One reason is that the most common neuroimmunological disease, multiple sclerosis, covered i
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