Accuracy evaluation of objective refraction using the wavefront aberrometer in pseudophakic eyes

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Accuracy evaluation of objective refraction using the wavefront aberrometer in pseudophakic eyes Min Hou 1 & Yujie Ding 1 & Liangping Liu 1 & Yanxin Xu 1 & Jianbing Li 1 & Mingxing Wu 1 Received: 19 March 2020 / Revised: 21 May 2020 / Accepted: 16 June 2020 # Springer-Verlag GmbH Germany, part of Springer Nature 2020

Abstract Purpose To evaluate the accuracy of wavefront-derived objective refraction in pseudophakic eyes. Methods Retrospective case series. A total of 356 eyes (356 patients) that underwent phacoemulsification and posterior chamber intraocular lens implantation were included. Noncycloplegic subjective manifest refraction (MR) and objective refraction results from the wavefront aberrometer were obtained and compared. Subgroup analysis of objective refraction at 2.6-mm zone was performed based on axial length (AL) and average keratometry. Results The biases (at the 2.6-mm, 3-mm, and 4-mm zones) were − 0.29 ± 0.37 D, − 0.53 ± 0.41 D, and − 0.51 ± 0.60 D for sphere; − 0.27 ± 0.36 D, − 0.52 ± 0.38 D, and − 0.53 ± 0.51 D for spherical equivalent (SE); 0.03 ± 0.20 D, 0.03 ± 0.22 D, and 0.04 ± 0.27 D for J0; and 0.01 ± 0.16 D, 0.03 ± 0.22 D, and 0.01 ± 0.22 D for J45, respectively. Objective refraction for sphere, SE, and J0 (at 2.6 mm, 3 mm, and 4 mm) was significantly different from MR (P < 0.05), while J45 values were equal. The objective refraction at 2.6 mm was the most accurate in short eyes (≤ 22.5 mm) with a minimum bias for SE (− 0.15 ± 0.28 D) and highest percentage of SE within ± 0.25 to ± 0.75 D of MR. However, there was no difference between the keratometry subgroups. Conclusions The wavefront aberrometer achieved the best accuracy at 2.6 mm in pseudophakic eyes with short AL. It still needs modification to be used as a substitute for MR in such patients. Keywords Accuracy . Objective refraction . Wavefront aberrometer . Pseudophakic eyes

Introduction Objective refraction is now widely used in the clinical practice of ophthalmology with the emergence of new machines for refraction. Many previous studies have evaluated the accuracy of an aberrometer for objective refraction. McGinnigle et al. reported the wavefront-derived technique provided valid and repeatable measures of objective refraction compared with noncycloplegic subjective manifest refraction (MR) in phakic eyes [1]. Jinabhai et al. demonstrated that wavefront Min Hou and Yujie Ding contributed equally to this work. Electronic supplementary material The online version of this article (https://doi.org/10.1007/s00417-020-04806-5) contains supplementary material, which is available to authorized users. * Mingxing Wu [email protected] 1

State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, No.7 Jinsui Road, Guangzhou, People’s Republic of China

aberrometry performed better in estimating refraction than did the subjective method in keratoconic eyes [2]. However, whether objective refraction obtained by a wavefront aberrometer is a sufficiently accurate substitute for subjective MR fo