Adalimumab
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Listeriosis: case report A 58-year-old woman with rheumatoid arthritis had been receiving adalimumab for 5 months when she was admitted with a 3-day history of severe diarrhoea and vomiting; her adalimumab dosage at that time was 40mg every 2 weeks. Her temperature was 38°C and she had hypovolaemia, hypotension and tachycardia. Listeria monocytogenes was identified in a blood culture on hospital day 3. She started a 2-week course of high-dose ampicillin and gentamicin. Her gastrointestinal and systemic symptoms rapidly resolved, and she was discharged soon after completing her antibacterial course. She remained well during follow-up with adalimumab removed from her treatment regimen. Murphy G, et al. Systemic listeriosis with adalimumab therapy. JCR: Journal of 801158332 Clinical Rheumatology 15: 369-370, No. 7, Oct 2009 - Ireland
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Reactions 9 Jan 2010 No. 1283
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