Added value of susceptibility-weighted imaging to diffusion-weighted imaging in the characterization of parotid gland tu
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Added value of susceptibility‑weighted imaging to diffusion‑weighted imaging in the characterization of parotid gland tumors Jia‑Suo Jiang1 · Liu‑Ning Zhu2 · Wei Chen1 · Lu Chen1 · Guo‑Yi Su1 · Xiao‑Quan Xu1 · Fei‑Yun Wu1 Received: 3 March 2020 / Accepted: 13 April 2020 © Springer-Verlag GmbH Germany, part of Springer Nature 2020
Abstract Purpose To assess the added value of susceptibility-weighted imaging (SWI) to diffusion-weighted imaging (DWI) in the characterization of parotid gland tumors. Methods Seventy-eight patients with pathologically confirmed parotid gland tumors, who underwent DWI and SWI for pre-surgery evaluation, were enrolled. Apparent diffusion coefficient (ADC) and degree of intratumoral susceptibility signal intensity (ITSS) were measured and compared between benign and malignant groups, and among pleomorphic adenoma (PA), Warthin tumor (WT) and malignant tumor (MT). Independent sample t test, one-way analysis of variance and receiver operating characteristic curve analysis were used for statistical analyses. Results Benign parotid gland tumor showed a significantly higher mean ADC value than malignant tumors (0.836 ± 0.350 vs 0.592 ± 0.163, p = 0.001). Setting an average ADC value of 0.679 as the cut-off value, optimal differentiating performance could be obtained (AUC, 0.700; sensitivity, 62.69%; specificity, 81.82%) for differentiating malignant from benign tumors. PA showed significantly higher mean ADC and less ITSS than WT (ADC, p
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