Adhesion G Protein-coupled Receptors Molecular, Physiological and Ph
Latest research on Adhesion GPCRs has unearthed surprising revelations about the events that govern the signal transduction of these receptor molecules and the cellular and organ requirements for these signals. Unexpected and unprecedented findings sugges
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Tobias Langenhan Torsten Schöneberg Editors
Adhesion G Protein-coupled Receptors Molecular, Physiological and Pharmacological Principles in Health and Disease
Handbook of Experimental Pharmacology
Volume 234 Editor-in-Chief J.E. Barrett, Philadelphia
Editorial Board V. Flockerzi, Homburg M.A. Frohman, Stony Brook, NY P. Geppetti, Florence F.B. Hofmann, M€unchen M.C. Michel, Ingelheim C.P. Page, London W. Rosenthal, Jena K. Wang, Beijing
More information about this series at http://www.springer.com/series/164
€neberg Tobias Langenhan • Torsten Scho Editors
Adhesion G Protein-coupled Receptors Molecular, Physiological and Pharmacological Principles in Health and Disease
Editors Tobias Langenhan Institute of Physiology Department of Neurophysiology University of W€urzburg W€ urzburg, Germany
Torsten Sch€ oneberg Institute of Biochemistry Medical Faculty University of Leipzig Leipzig, Germany
ISSN 0171-2004 ISSN 1865-0325 (electronic) Handbook of Experimental Pharmacology ISBN 978-3-319-41521-5 ISBN 978-3-319-41523-9 (eBook) DOI 10.1007/978-3-319-41523-9 Library of Congress Control Number: 2016955552 # Springer International Publishing AG 2016 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper This Springer imprint is published by Springer Nature The registered company is Springer International Publishing AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland
Preface
The very first monograph that was dedicated to a general overview on the adhesion family of G protein-coupled receptors (aGPCRs) was published just in 2010 (Adhesion-GPCRs: Structure to Function. Yona and Stacey, Ed., Landes Bioscience and Springer). It was the earliest attempt by a small group of researchers to cast the scarce information on these enigmatic molecules into a general concept on what they do and how they do it. The absence of such public face for the biology of aGPCRs was painfully felt by all colleagues who were actively researching aG
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