Adipose Tissue Biology

The past decade has seen an exponential increase in our knowledge and understanding of adipose tissue biology. This has coincided with the continued rise in obesity across all generations. Clearly despite substantial advances in research into adipose tiss

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Adipose Tissue Biology Second Edition

Adipose Tissue Biology

Michael E. Symonds Editor

Adipose Tissue Biology Second Edition

Editor Michael E. Symonds Academic Division of Child Health The School of Medicine, The University Hospital Queen’s Medical Centre Nottingham, UK

ISBN 978-3-319-52029-2    ISBN 978-3-319-52031-5 (eBook) DOI 10.1007/978-3-319-52031-5 Library of Congress Control Number: 2017934889 © Springer Science+Business Media LLC 2017 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper This Springer imprint is published by Springer Nature The registered company is Springer Science+Business Media LLC The registered company address is: 233 Spring Street, New York, NY 10013, U.S.A.

Contents

1 The Evolution of Mammalian Adipose Tissues..................................... 1 Caroline M. Pond 2 Adipocyte Progenitors from Human Pluripotent Stem Cells.............. 61 A.-L. Hafner and C. Dani 3 Adipocyte Differentiation........................................................................ 69 José María Moreno-Navarrete and José Manuel Fernández-Real 4 Brown Adipose Tissue.............................................................................. 91 Martin Klingenspor, Andrea Bast, Florian Bolze, Yongguo Li, Stefanie Maurer, Sabine Schweizer, Monja Willershäuser, and Tobias Fromme 5 White Adipose Tissue............................................................................... 149 Stephane Gesta and C. Ronald Kahn 6 The Physiological Significance of Brown Adipose Tissue and the Beiging of White Adipose Tissue in People.............................. 201 Maria Chondronikola and Labros S. Sidossis 7 Macrophages and Inflammation............................................................ 229 Elise Dalmas, Joan Tordjman, Michèle Guerre-Millo, and Karine Clément 8 Sex Differences in Body Fat Distribution............................................... 257 Mohamed Fouad Mansour, Chon-Wai Jeremy Chan, Sofia Laforest, Alain Veilleux, and André