Adrenal Actions on Brain
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Adrenal Actions on Brain Editors
D. Ganten and D. Pfaff Contributors T. Baker U. Beckford B. Bohus E. R. De Kloet A. J. Doupe B. Gillham B. D. Greenstein M. C. Holmes M. T. Jones B. S. McEwen P.H. Patterson W.F. Riker, Jr. A. Sastre H. D. Veldhuis
With 25 Figures
Springer-Verlag Berlin Heidelberg New York 1982
Editors Dr. DETLEV GANTEN, M.D., Ph.D. Pharmakologisches Institut UniversiHit Heidelberg 1m Neuenheimer Feld 366 0-6900 Heidelberg/FRG Dr. DONALD PFAFF, Ph.D. Rockefeller University Y ork Avenue, and 66 th Street New York, NY lO021/USA
The picture on the cover has been taken from Nieuwenhuys R., Voogd J., van Huijzen Chr.: The Human Central Nervous System. 2nd Edition. Springer-Verlag Berlin Heidelberg New York 1981
ISBN-13: 978-3-642-68338-1 e-ISBN -13: 978-3-642-68336-7 DOl: 10.1007/978-3-642-68336-7 Library of Congress Cataloging in Publication Data. Main entry under title: Adrenal action on brain. (Current topics in neuroendocrinology; 2) Bibliography: p. Includes index. I. adrenocortical hormones - Physiological effect. 2. Brain. 3. Glucocorticoids - Physiological effect. I. Ganten, D. (Detlev), 1941. II. Pfaff, Donald W., 1939. III. Series [DNLM: I. Adrenal cortex hormones Physiology. 2. Brain - Drug effects. WI CU82Qv.2/WK 755 A242] QP572.A3A37 599.01'88 82-754 AACR2 This work is SUbjected to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically those of translation, reprinting, re-use of illustrations, broadcasting, reproduction by photocopying machine or similar means, and storage in data banks. Under § 54 of the German Law where copies are made for other than private use, a fee is payable to "Verwertungsgesellschaft Wort", Munich.
© by Springer-Verlag Berlin Heidelberg 1982 Softcover reprint of the hardcover 1st edition 1982 The use of registered names, trademarks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. 2121/3130-543210
Contents
Glucocorticoids and Hippocampus: Receptors in Search of a Function By B.S. McEwen With 8 Figures
1
Glucocorticoids and the Developing Nervous System By A.J. Doupe and P.H. Patterson . . . . . . . . . . . . . . . . . . . . . . 23 Feedback Actions of Adrenal Steroid Hormones By M.T. Jones, B. Gillham, B.D. Greenstein, U. Beckford, and M.C. Holmes With 9 Figures . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 45 Electrophysiologic and ainical Aspects of Glucocorticoids on Certain Neural Systems By W.F. Riker, Jr., T. Baker, and A. Sastre With 6 Figures . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 69 Adrenal Steroids and Behavioral Adaptation: Relationship to Brain Corticoid Receptors By B. Bohus, E.R. De Kloet, and H.D. Veldhuis With 2 Figures . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 107 Subject Index
149
Glucocorticoids and Hippocampus: Receptors in Search of a Function BRUCE S. M