Advances in Mercury Toxicology

This book is based on an international meeting organized by the University of Tokyo and the University of Rochester, and is published as one belonging to the series of Rochester International Conferences in Environmental Toxicity. The meeting on "Advances

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ROCHESTER SERIES ON ENVIRONMENTAL TOXICITY Series Editors: Thomas W. Clarkson and Morton W. Miller ADVANCES IN MERCURY TOXICOLOGY

Edited by Tsuguyoshi Suzuki, Nobumasa Imura, and Thomas W. Clarkson

BIOLOGICAL MONITORING OF TOXIC METALS

Edited by Thomas W. Clarkson, Lars Friberg, Gunnar F. Nordberg, and Polly R. Sager

THE CYTOSKELETON: A Target for Toxic Agents

Edited by Thomas W. Clarkson, Polly R. Sager, and Tore L. M. Syversen

REPRODUCTIVE AND DEVELOPMENTAL TOXICOLOGY OF METALS

Edited by Thomas W. Clarkson, Gunnar F. Nordberg, and Polly R. Sager

A Continuation Order Plan is available for this series. A continuation order will bring delivery of each new volume immediately upon publication. Volumes are billed only upon actual shipment. For further information please contact the publisher.

Advances in Mercury Toxicology Edited by

Tsuguyoshi Suzuki

University of Tokyo Tokyo, Japan

Nobumasa Imura

Kitasoto University Tokyo, Japan

and

Thomas W. Clarkson

University of Rochester School of Medicine Rochester, New York

Springer Science+Business Media, LLC

Library of Congress Catalog1ng-1n-PublIcatlon Data

Advances in mercury toxicology / edited by Tsuguyoshi Suzuki, Nobumasa Imu^a, and Thomas W. Clarkson. p. cm. — (Rochester series on environmental toxicity) "Proceedings of a Rochester International Conference in Environmental Toxicity, held August 1-3, 1990 in Tokyo, J a p a n " — T . p . verso. Includes bibliographical references and index. 1. M e r c u r y — T o x i c o l o g y — C o n g r e s s e s . I. Suzuki, Tsuguyoshi, 1932II. Imura, Nobumasa, 1935. III. Clarkson, Thomas W. IV. Rochester International Conference on Environmental Toxicity (19th . 1390 . Tokyo, Japan) V. Series. [DNLM: 1. Environmental P o l l u t a n t s — a d v e r s e e f f e c t s — c o n g r e s s e s . 2. Mercury Poisoning—congresses. QV 293 A244] RA1231.M5A34 1991 615.9'25—dc20 DNLM/DLC 91-45506 for Library of Congress CIP

Proceedings of a Rochester International Conference in Environmental Toxicity, held August 1-3, 1990, in Tokyo, Japan ISBN 978-1-4757-9073-3 DOI 10.1007/978-1-4757-9071-9

ISBN 978-1-4757-9071-9 (eBook)

© Springer Science+Business Media New York 1991 Originally published by Plenum Press, New York in 1991 Softcover reprint of the hardcover 1st edition 1991 All rights reserved No part of this book may be reproduced, stored in a rëtrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying, microfilming, recording, or otherwise, without written permission from the Publisher

Conference Coordinators Seiichiro Himeno Kitasato University Tokyo, Japan and

Michael A. Terry University of Rochester School of Medicine Rochester, New York

Sponsored by Japan Society for the Promotion of Science Inoue Foundation for Science University of Tokyo National Science Foundation (INT - 8915129) leOH Subcommittee of Toxicology of Metals

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We gratefully acknowledge additional support from the following contributors: Banyu Pharmaceutical Company, Ltd. Chugai Pharmaceutical Company, Lt