Amphotericin B
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Hypokalaemia, thrombocytopenia and allergic reactions in a child: case report An 8-year-old boy presented with an 11-month history of fever, anorexia, night sweats, vomiting and weight loss; he was diagnosed with visceral leishmaniasis. He received amphotericin B [dosage and route not stated] but developed severe hypokalaemia, thrombocytopenia and allergic reactions [time to reaction onset not stated]. Amphotericin B was discontinued and replaced with miltefosine. Within 1 week, his fever had resolved, his appetite improved and he started to gain weight. However, he later developed a nosocomial infection and died. Humayun KN, et al. Use of miltefosine in the treatment of visceral leishmaniasis in children at a tertiary care hospital of Karachi. Journal of the Pakistan Medical 803028599 Association 66: 489-491, No. 6, Jun 2010 - Pakistan
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Editorial comment: This article included details of a second patient with visceral leishmaniasis, but this patient did not receive amphotericin B.
0114-9954/10/1312-0001/$14.95 © 2010 Adis Data Information BV. All rights reserved
Reactions 31 Jul 2010 No. 1312
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