Analytical ultracentrifugation: still the gold standard that offers multiple solutions

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EDITORIAL

Analytical ultracentrifugation: still the gold standard that offers multiple solutions Renwick C. J. Dobson1,2 · Trushar R. Patel3 Published online: 19 November 2020 © European Biophysical Societies’ Association 2020

Abstract Understanding the nature of macromolecules and their interactions in solution underpins many fields, including biology, chemistry and materials science. The 24th International Analytical Ultracentrifugation Workshop and Symposium (AUC2019, held in Christchurch, New Zealand, August 2019), brought together 77 international delegates to highlight recent developments in the field. There was a focus on analytical ultracentrifugation, although we recognise that this is but one of the key methods in the biophysicist’s toolkit. Many of the presentations showcased the versatility of analytical ultracentrifugation and how such experiments are integrated with other solution techniques, such as small-angle X-ray scattering, cryo-electron microscopy, isothermal titration calorimetry and more. This special issue emphasises a wide range of themes covered in the meeting, including carbohydrate chemistry, protein chemistry, polymer science, and macromolecular interactions.

Introduction and conference organisation On a crisp spring morning in late August, Christchurch, New Zealand, gathered a ‘rotor’ (the collective noun) of biophysicists with a shared interest in the solution behaviour of biomolecules and polymers, and a focus on analytical ultracentrifugation (AUC). They had come together for AUC2019, the 24th International Analytical Ultracentrifugation Workshop and Symposium, to discuss and celebrate recent developments in the field. As chair of the organising committee, Ren Dobson is very grateful to the 77 delegates who attended the event, most of whom were from Europe, North America, or Asia, and had made the long trip out to New Zealand (in some cases over * Renwick C. J. Dobson [email protected] * Trushar R. Patel [email protected] 1



Biomolecular Interaction Centre and School of Biological Sciences, University of Canterbury, PO Box 4800, Christchurch 8140, New Zealand

2



Bio21 Molecular Science and Biotechnology Institute, Department of Biochemistry and Molecular Biology, University of Melbourne, Parkville, VIC 3010, Australia

3

Department of Chemistry and Biochemistry, Alberta RNA Research and Training Institute, University of Lethbridge, Lethbridge, AB T1K 3M4, Canada



2 days!). This was just the second time the meeting had been held in the southern hemisphere, but we hope not the last. A special mention and thanks to the committees that helped shape AUC2019. The scientific organising committee had a strong international flavour, comprising Sarah Atkinson (Monash University, Australia), Olwyn Byron (University of Glasgow, UK), Helmut Cölfen (Universität Konstanz, Germany), Luitgard Nagel-Steger (Heinrich Heine Universität, Germany), Phillip Koldewey (F. Hoffmann-La Roche Ltd, Basel, Switzerland), Alexandra Solovyova (Newcastle University, UK), Borries Demele