ANCA-Associated Vasculitides Immunological and Clinical Aspects
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ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY Editorial Board: NATHAN BACK, State University of New York at Buffalo IRUN R. COHEN, The Weizmann Institute of Science DAVID KRITCHEVSKY, Wistar Institute
ABEL LAJTHA, N. S. Kline Institute for Psychiatric Research RODOLFO PAOLETTI, University of Milan
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ANCA-ASSOCIATED VASCULITIDES Immunological and Clinical Aspects
Edited by
Wolfgang L. Gross Medical University of Liibeck Liibeck, Germany and Rheumaklinik Bad Bramstedt GmbH Bad Bramstedt, Germany
SPRINGER SCIENCE+BUSINESS MEDIA, LLC
Library of Congress Catalogtng- tn- Publtcatton Data
ANCA-assoctated vasculi tides 1amunolog 1cal and cl 1n1 c a l aspects ed i ted by Wol fgang L. Gross. p. en. -- 10 kg
CLINICAL I Weight loss
3 Peripheral neuropathy 4 Myalgias
COMMENTS
DIAGNOSTIC CRITERIA
Table 1. Diagnostic criteria of polyarteritis nodosa.
Many French centers participated in these studies, mainly Departments of Internal Medicine but also Departments of Rheumatology, Nephrology, Pneumology, etc. Different subgroups of PN were studied: classic PN (cPN) with or without HBV infection and CSS. No patient presented only rapidly progressive glomerulonephritis due to microscopic PN without any systemic symptoms indicating its association with cPN. The first trial started in August 1980, and ended in December, 1983. It compared prednisone and PE (group 1A; 39 patients) to prednisone, CY and PE (group 1B; 32 patients). In this study PN patients were included without consideration for HBV serology. Between January, 1984, and December, 1988, 111 patients were included in 2 simultaneous trials, 78 in the group without HBV markers, and 33 in the trial organized for patients with HBV infection. Patients wi
