Anemia and Quality of Life: Association with Diagnosis and Treatment of Anemias
Anemia appears to have a direct effect on health-related quality of life across the spectrum of many disease conditions. The presence of anemia has been linked to frailty, functional impairment, mobility impairment, and falls in older persons. The chief
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Frequency of Anemia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1883
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Association of Anemia with Disease . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1883
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Impact of Treating Anemia on Quality of Life Measures . . . . . . . . . . . . . . . . . . . . . . . . . 1886
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Iron Deficiency Anemia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1887
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Post-Operative Anemia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1887
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Anemia and Chronic Kidney Disease . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1887
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Anemia and Cancer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1889
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Chemotherapy Induced Anemia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1889
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Anemia and Hematological Malignancies . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1889
10 Anemia and Cardiovascular Disease . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1890 11 Anemia and AIDS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1890 12 Anemia and Rheumatoid Arthritis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1890 13 Difficulties with Measuring Quality of Life and Anemia . . . . . . . . . . . . . . . . . . . . . . . . . 1890 14 Summary and Conclusions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1891 Summary Points . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1891
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Anemia and Quality of Life: Association with Diagnosis and Treatment of Anemias
Abstract: > Anemia appears to have a direct effect on health-related quality of life across the spectrum of many disease conditions. The presence of anemia has been linked to frailty, functional impairment, mobility impairment, and falls in older persons. The chief reasons for this rise in both incidence and prevalence of anemia with aging are gender-related changes in sex hormones and the accumulation of comorbid conditions. Anemia also appears to be an independent predictor of mortality, whether or not there is an associated underlying disease. List of Abbreviations: AIDS, acquired immunodeficiency syndrome; KDQ, kidney disease questionnaire; KS, Karnofsky scale; LASA, linear analog scale assessment; MOS-HIV, medical outcomes study in human immunodeficiency virus; QOL, quality of life; SF-36, short form-3
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