Animal Models of Ophthalmic Diseases
This book describes experimental animal models that mimic common human ocular diseases: herpetic keratitis, cataract, glaucoma, age-related macular degeneration, diabetic retinopathy, uveitis, retinitis pigmentosa, Graves’ disease, and intraocular tumors.
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Series Editor Arun D. Singh Cleveland, Ohio, USA
Essentials in Ophthalmology aims to promote the rapid and efficient transfer of medical research into clinical practice. It is published in four volumes per year. Covering new developments and innovations in all fields of clinical ophthalmology, it provides the clinician with a review and summary of recent research and its implications for clinical practice. Each volume is focused on a clinically relevant topic and explains how research results impact diagnostics, treatment options and procedures as well as patient management. The reader-friendly volumes are highly structured with core messages, summaries, tables, diagrams and illustrations and are written by internationally well-known experts in the field. A volume editor supervises the authors in his/her field of expertise in order to ensure that each volume provides cutting-edge information most relevant and useful for clinical ophthalmologists. Contributions to the series are peer reviewed by an editorial board. More information about this series at http://www.springer.com/series/5332
Chi-Chao Chan Editor
Animal Models of Ophthalmic Diseases
1C
Editor Chi-Chao Chan National Eye Institute National Institutes of Health Bethesda Maryland USA Zhongshan Ophthalmic Center Sun Yat-sen University Guangzhou China
ISSN 1612-3212 ISSN 2196-890X (electronic) Essentials in Ophthalmology ISBN 978-3-319-19433-2 ISBN 978-3-319-19434-9 (eBook) DOI 10.1007/978-3-319-19434-9 Library of Congress Control Number: 2015953321 Springer Cham Heidelberg New York Dordrecht London © Springer International Publishing Switzerland 2016 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper Springer International Publishing AG Switzerland is part of Springer Science+Business Media (www.springer.com)
Foreword
The relatively recent development of therapeutics to treat and eventually cure disease has a trajectory built on the long historical relationship between basic (or
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