Antimicrobial Coatings and Modifications on Medical Devices
Based on a fundamental understanding of the interaction between bacteria and materials, this timely volume emphasizes the latest research in the antimicrobial interfacial design and provides an invaluable blueprint for improving antimicrobial performance
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imicrobial Coatings and Modifications on Medical Devices
Antimicrobial Coatings and Modifications on Medical Devices
Zheng Zhang • Victoria E. Wagner Editors
Antimicrobial Coatings and Modifications on Medical Devices
Editors Zheng Zhang Global Advanced Engineering Teleflex Inc. Cambridge, MA, USA
Victoria E. Wagner Global Advanced Engineering Teleflex Inc. Cambridge, MA, USA
ISBN 978-3-319-57492-9 ISBN 978-3-319-57494-3 (eBook) DOI 10.1007/978-3-319-57494-3 Library of Congress Control Number: 2017941198 © Springer International Publishing AG 2017 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Printed on acid-free paper This Springer imprint is published by Springer Nature The registered company is Springer International Publishing AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland
Preface
Modifying medical devices with antimicrobial coatings and biomaterials is one of the most effective approaches to prevent device-associated infections. This book explores current and emerging antimicrobial technologies, biofilm-related evaluation techniques, and regulatory challenges, with particular emphasis on the coatings and modifications on medical devices. An overview of antimicrobial technologies on critical care implants followed by the public health and the regulatory science challenges associated with these devices are discussed. Progress in characterization and evaluation of infection on medical devices, such as diagnostic assays evaluating cell adhesion and biofilm formation including molecular-based approaches, is introduced. This book covers coatings and modifications incorporating various antimicrobial agents, including traditional antibiotics and antiseptic agents, as well as alternative agents through “anti-antibiotic” approaches. Delivering antimicrobial agents with porous materials is introduced afterwards as an
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