Applying Comparative Effectiveness Data to Medical Decision Making
This textbook introduces students to the basic concepts and methods used to measure and compare the expected benefits, risks and cost of preventive and therapeutic medical interventions. It provides an easily accessible overview of comparative effectivene
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Applying Comparative Effectiveness Data to Medical Decision Making A Practical Guide
Applying Comparative Effectiveness Data to Medical Decision Making
Carl V. Asche Editor
Applying Comparative Effectiveness Data to Medical Decision Making A Practical Guide
Adis
Editor Carl V. Asche Research Professor, Director of Center for Outcomes Research Department of Pharmacy Systems, Outcomes and Policy Affiliate Faculty, Center for Pharmacoepidemiology and Pharmacoeconomic Research, University of Illinois at Chicago College of Pharmacy Chicago, IL USA Research Affiliate Centre on Aging, University of Victoria Victoria British Columbia
ISBN 978-3-319-22064-2 ISBN 978-3-319-23329-1 DOI 10.1007/978-3-319-23329-1
(eBook)
Library of Congress Control Number: 2015956409 Springer Cham Heidelberg New York Dordrecht London © Springer International Publishing Switzerland 2016 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper Adis is a brand of Springer Springer International Publishing AG Switzerland is part of Springer Science+Business Media (www.springer.com)
Contents
1
Introduction to Comparative Effectiveness Research . . . . . . . . . . . . . . . 1 Carmen S. Kirkness
2
Randomized Controlled Trials . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13 Nikhil R. Kalva and James F. Graumlich
3
Observational Studies . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 27 Jaeyong Bae and Carl V. Asche
4
Evaluating Published CER Evidence . . . . . . . . . . . . . . . . . . . . . . . . . . . 37 Jinma Ren
5
Epidemiological Principles Applied to CER. . . . . . . . . . . . . . . . . . . . . . 53 Jinma Ren
6
The Question of Value. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 63 Minchul Kim, Carl V. Asche, and Inkyu K. Kim
7
Medical Decision Making: When Evidence and Medical Culture Clash . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 83 Andy Bland and B
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