Decision Making in a World of Comparative Effectiveness Research A P

In the past decade there has been a worldwide evolution in evidence-based medicine that focuses on real-world Comparative Effectiveness Research (CER) to compare the effects of one medical treatment versus another in real world settings. While most of thi

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Decision Making in a World of Comparative Effectiveness Research A Practical Guide

Decision Making in a World of Comparative Effectiveness Research

Howard G. Birnbaum  •  Paul E. Greenberg Editors

Decision Making in a World of Comparative Effectiveness Research A Practical Guide

Editors Howard G. Birnbaum Analysis Group, Inc. Boston Massachusetts USA

Paul E. Greenberg Analysis Group, Inc. Boston Massachusetts USA

ISBN 978-981-10-3261-5    ISBN 978-981-10-3262-2 (eBook) DOI 10.1007/978-981-10-3262-2 Library of Congress Control Number: 2017941182 © Springer Nature Singapore Pte Ltd. 2017 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Printed on acid-free paper This Adis imprint is published by Springer Nature The registered company is Springer Nature Singapore Pte Ltd. The registered company address is: 152 Beach Road, #21-01/04 Gateway East, Singapore 189721, Singapore

Acknowledgements

Howard G. Birnbaum and Paul E. Greenberg gratefully acknowledge our Analysis Group colleagues who were instrumental in effectively coordinating with the authors of the chapters in this book. We also want to thank all of the authors for their significant contributions. This book was made possible by their collective experience and detailed subject matter knowledge. Editing assistance was provided by Renata Cavalier, MA; Lucia Antras, PhD; Ana Bozas, PhD; and Cinzia Metallo, PhD, employees of Analysis Group, Inc. In particular, Renata Cavalier diligently worked through all the numerous issues in organizing and coordinating each of the chapters into a consistently formatted book.

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Contents

Part I  Introduction 1 Introducing Decision Making in a World of Comparative Effectiveness Research����������������������������������������������������������������������������������  3 Howard G. Birnbaum and Paul E. Greenberg 2 Perspectives of Comparative Effectiveness Researc