Arterial Disorders Definition, Clinical Manifestations, Mechanisms a
As our knowledge about arterial disease is greatly expanding, the aim of this book is to explore all aspects of arterial pathology, including classification, clinical manifestations, pathogenesis, and therapeutic options. The discussion of pathophysiologi
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Arterial Disorders Definition, Clinical Manifestations, Mechanisms and Therapeutic Approaches
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Arterial Disorders
Adel Berbari • Giuseppe Mancia Editors
Arterial Disorders Definition, Clinical Manifestations, Mechanisms and Therapeutic Approaches
Editors Adel Berbari American University of Beirut Medical Center Beirut Lebanon
Giuseppe Mancia University of Milano Bicocca IRCCS Istituto Auxologico Italiano Milan Italy
ISBN 978-3-319-14555-6 ISBN 978-3-319-14556-3 DOI 10.1007/978-3-319-14556-3
(eBook)
Library of Congress Control Number: 2015935349 Springer Cham Heidelberg New York Dordrecht London © Springer International Publishing Switzerland 2015 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com)
Preface
Cardiovascular disorders account for the increased morbidity and mortality that accompanies a large number of diseases, including diabetes mellitus, obesity, hypertension, nephropathies and rheumatoid arthritis. Recent progress in knowledge has led to an increased understanding of the pathophysiologic mechanisms that underlie vascular alterations in these diseases, the evidence being that a wide range of factors are likely to participate to a variable degree in each of them. Aim of this book is to describe the physiology of macro- and microcirculation together with their interactions. It is also to discuss the structural and functional alterations that macro- and microcirculation develop with diseases, with attention to their hemodynamic, metabolic, humoral, hormonal, inflammatory, as well as genetic or environmental nature. Emphasis is placed on recent notions, such as the involvement of arterial stiffness in the initiation and progression of atherosclerosis, as well as in the age-related alterations of systemic and renal vasculature; the importance of mineral-bone-vascular interactions; the diagnostic and prognostic significance of new noninvasive measures of va
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