Assessment of tuberculosis situation in Cairo governorate from 2006 to 2012 after application of directly observed thera

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Assessment of tuberculosis situation in Cairo governorate from 2006 to 2012 after application of directly observed therapy short-course strategy Sherif A. Eissa, Ali A. Okab, Tarek S. Essawy, Eman A. El Ghany Background  Directly observed therapy short course (DOTS) is a strategy in which a trained healthcare worker or a designated individual provides the prescribed antituberculous drugs and watches the patient to ensure the patient is taking each dose. Aim  The objective of this work was to study tuberculosis situation in Cairo governorate from 2006 to 2012 after application of DOTS. Methodology  This was a retrospective clinical cohort study carried out at the Cairo governorate. Results  Percentages of cure and complete treatment were 61.6 and 20.4%, respectively. The incidence of failure, death, default, and transfer

Introduction Tuberculosis (TB) remains to be a major global health problem. It causes ill-health among millions of people each year and ranks as the second leading cause of death from an infectious disease worldwide, after the HIV. The latest estimates included in this report are that there were 8.6 million new TB cases in 2012 and 1.3 million TB deaths (1.0 million deaths among HIV-negative individuals and 0.3 million HIV-associated TB deaths). Most of these TB cases and deaths occur among men, but the burden of disease among women is also high [1]. The new post-2015 global TB strategy aims to end the targets to reduce TB deaths by 95% and to cut new cases by 90% between 2015 and 2035, and to ensure that no family is burdened with the catastrophic expenses due to TB. The resolution calls on governments to adapt and implement the strategy with high-level commitment and financing. It reinforces a focus within the strategy on serving populations highly vulnerable to infection and poor healthcare access, such as migrants [2]. Directly observed therapy short course (DOTS) is a strategy in which a trained healthcare worker or a designated individual provides the prescribed antituberculous drugs and watches the patient to ensure the patients is taking each dose [3]. The main goals of TB treatment are to cure individuals with the disease and minimize the transmission of Mycobacterium tuberculosis to others in the community [4]. Major

out decreased after DOTS (2.2, 4.5, 8.6, and 2.7, respectively). Conclusion  The introduction of DOTS in the Cairo governorate has led to a treatment success rate of 82% (nearly similar to the WHO target of ‘85%’). Egypt J Broncho 2016 10:52–57 © 2016 Egyptian Journal of Bronchology. Egyptian Journal of Bronchology 2016 10:52–57 Keywords: Cairo, DOTS, tuberculosis Department of Chest Diseases Correspondence to Tarek S. Essawy, MD, Benha University Hospital, Benha, Egypt E-mail: [email protected] Received 24 June 2015 Accepted 28 July 2015

progress in global TB control followed the widespread implementation of the DOTS strategy. The Stop TB Strategy, launched in 2006, builds upon and enhances the achievements of DOTS. The five components of DOTS are as follows: sustained