Atlas of Diabetes Fourth Edition

Diabetes mellitus is increasing in incidence, prevalence, and importance as a chronic disease throughout the world. The International Diabetes Federation projects that by 2030 there will be 438 million people with diabetes on a global scale. In the United

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Atlas of

Diabetes Fourth Editon Edited by

Jay S. Skyler, MD, MACP Diabetes Research Institute University of Miami Miller School of Medicine Miami, FL, USA

Editor Jay S. Skyler, MD, MACP Professor of Medicine, Pediatrics, and Psychology University of Miami Miller School of Medicine Deputy Director, Clinical Research & Academic Programs Diabetes Research Institute 1450 NW 10th Avenue, Suite 3054 Miami, FL 33136, USA [email protected]

ISBN 978-1-4614-1027-0 e-ISBN 978-1-4614-1028-7 DOI 10.1007/978-1-4614-1028-7 Springer New York Dordrecht Heidelberg London Library of Congress Control Number: 2011941604 © Springer Science+Business Media, LLC 2012 All rights reserved. This work may not be translated or copied in whole or in part without the written permission of the publisher (Springer Science+Business Media, LLC, 233 Spring Street, New York, NY 10013, USA), except for brief excerpts in connection with reviews or scholarly analysis. Use in connection with any form of information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed is forbidden. The use in this publication of trade names, trademarks, service marks, and similar terms, even if they are not identified as such, is not to be taken as an expression of opinion as to whether or not they are subject to proprietary rights. While the advice and information in this book are believed to be true and accurate at the date of going to press, neither the authors nor the editors nor the publisher can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the material contained herein. Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com)

Preface Diabetes mellitus is increasing in incidence, prevalence, and importance as a chronic disease throughout the world. The International Diabetes Federation projects that by 2030 there will be 552 million people with diabetes on a global scale. In the USA, the Centers for Disease Control calculates that 25.8 million people (or 8.3% of the population) have diabetes and nearly 2 million Americans develop diabetes each year. Thus, the burden of diabetes is enormous in terms of the magnitude of the population affected. Among those under 20 years of age, the disease pattern is changing rapidly. One out of every 300–400 children and adolescents has type 1 diabetes. The incidence of type 1 diabetes is sky-rocketing, particularly in children less than 5 years of age. In addition, the incidence of type 2 diabetes among adolescents has increased 15- to 20-fold since 1982. Indeed, the average age of onset of type 2 diabetes is dropping. With more people developing the disease in their teens, 20s, and 30s, their lifetime potential for complications is dramatically increased. Strikingly, although type 2 diabetes is increasing among the young, its burden on older patients is growing as well.