Atmospheric Pressure Dielectric Barrier Discharges for the Deposition of Organic Plasma Polymer Coatings for Biomedical
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Atmospheric Pressure Dielectric Barrier Discharges for the Deposition of Organic Plasma Polymer Coatings for Biomedical Application Jumal Ibrahim1,2,3 · Sameer A. Al‑Bataineh1,4 · Andrew Michelmore1,2 · Jason D. Whittle1,2,3 Received: 16 December 2019 / Accepted: 23 October 2020 © Springer Science+Business Media, LLC, part of Springer Nature 2020
Abstract Atmospheric pressure dielectric barrier discharges (DBDs) are proving to have great potential in the bioengineering and medical field for functionalisation of biomaterials. The ability to operate in open atmosphere in a continuous process makes DBD a preferred method over conventional surface engineering techniques and low pressure plasma material processing. DBDs are characterised by configurations with a dielectric layer between conducting electrodes in the discharge path. The success in the application of DBDs in the modification of biomaterials has been demonstrated in many research articles. This review surveys DBD plasma-based methods for the production of organic polymer coatings on biomaterials that contain reactive chemical species useful for subsequent biomedical application. In the first part of this paper, a general introduction in the field of surface engineering will be given. The review then focuses on a brief overview of plasma-based deposition techniques including those of atmospheric plasmas. A brief knowledge of the operation and formation of DBDs are then presented. The application of DBDs for the deposition of coatings with different functionalities and for different biomedical applications are reviewed. The current challenges related to the discharge characteristics and thin organic coatings specific to stability and ageing processes are also discussed. Keywords Dielectric barrier discharge · Plasma polymer coating · Atmospheric pressure · Biomedical application
* Jason D. Whittle [email protected] 1
University of South Australia, UniSA STEM, Adelaide, SA 5000, Australia
2
Future Industries Institute, University of South Australia, Adelaide, SA 5000, Australia
3
Cooperative Research Centre for Cell Therapy Manufacturing (CRC-CTM), Adelaide, SA 5000, Australia
4
TekCyte Pty Ltd, University of South Australia, Mawson Lakes 5095, Australia
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Plasma Chemistry and Plasma Processing
Introduction and Background The increasing demand for materials with improved performances has driven the careful engineering of smart, functional materials tailored according to specific applications. Prudent engineering of such materials increases their performance, improves usage efficiency and helps to create and enhance surfaces with desired interfacial physico-chemical properties [1]. Surface modification of materials has, therefore, become crucial in biological and biomedical applications, especially where better cell adhesion and cell responses are desired. Surface engineering may involve physical treatment/adsorption [2], chemical treatment [3], vapour deposition techniques [4, 5], heat/flame treatment [6, 7] and
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