Basic research on countermeasures against barium sulfate aggregation using a gastric phantom
The principal aim of this study was to conduct basic experiments to examine countermeasures against barium sulfate aggregation caused by denture adhesive in gastric cancer screening test. Experiment 1; barium sulfate aggregation was reconstructed in petri
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of Radiology, Osaka Center for Cancer and Cardiovascular Disease Prevention, Osaka, Japan 2Department of Nursing, Senrikinran University, Suita, Japan 3Okayama University, Graduate School of Health Sciences, Okayama, Japan 4Butsuryo College of Osaka, Sakai, Japan 5Department of Clinical nutrition, Suzuka University of Medical Science, Suzuka, Japan 6Faculty of Health Science and Technology, Kawasaki University of Medical Welfare, Okayama, Japan 7Department of Radiology, Osaka Medical Center and Research Institute for Maternal and Child Health, Izumi, Japan 8 Osaka Kyoiku University (Professor Emeritus), Kashiwara, Japan Abstract— The principal aim of this study was to conduct basic experiments to examine countermeasures against barium sulfate aggregation caused by denture adhesive in gastric cancer screening test. Experiment 1 ; barium sulfate aggregation was reconstructed in petri dishes and the degree of reducing aggregation by seven types of commercial drink and tap water was assessed visually. The most effective one was tap water. Experiment 2 ; two types of aggregation (severe and mild aggregation) were reconstructed using gastric phantom BMU-1, tap water of 30-150ml was added and the degree of reducing aggregation was assessed with the images. In the case of severe aggregation, the most effective quantity of tap water was 120 ml and the next was 150 ml with the following of 90, 60 and 30 ml (P < 0.05). In the case of mild aggregation, the order of effective quantity was 90, 60, 120, 30 and 150 ml (P < 0.05). The results of this study suggested that tap water drinking of the subject was effective for the reduction of barium sulfate aggregation in gastric cancer screening and the most effective quantity of tap water was 120 ml in the case of severe aggregation and 90 ml in the case of mild aggregation. Keywords— gastric cancer screening, barium sulfate aggregation, denture adhesive, tap water
I. INTRODUCTION
Based on the evidence of reduced mortality, gastric cancer screening and gastroscopic examination have been widely recognized to be effective against the desease. In Japan, approximately six million persons annually receive the screening as a countermeasure “standard radiography I” (ST I) or a voluntary screening “standard radiography II” (ST II). ST I and ST II are based on the New Gastric Radiographic Guidelines, Revised Edition (2011) of the Japanese Society of Gastrointestinal Cancer Screening. In each radiography, highdensity (200 w/v % or higher) low-viscosity barium sulphate powder is used as a contrast agent and foaming agent (5 g) is also used to perform the examination. © Springer Nature Singapore Pte Ltd. 2018 H. Eskola et al. (eds.), EMBEC & NBC 2017, IFMBE Proceedings 65, DOI: 10.1007/978-981-10-5122-7_169
To date, many studies have reported the utility of highdensity low-viscosity barium sulfate [1], but several adverse events have also reported. They are an increased risk of aspiration accidents [2], outflow to the duodenum, intestinal perforation and peritonitis, exposure of the subjects
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