Basics of PET Imaging Physics, Chemistry, and Regulations
This revised edition of Basics of PET Imaging presents an unparalleled text on the basics of PET imaging technology. Distinguished author, Dr. Gopal B. Saha, has updated his previous bestselling work with concise chapters on PET fundamentals, including: B
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Gopal B. Saha, PhD Department of Nuclear Medicine, The Cleveland Clinic Foundation, Cleveland, Ohio
Basics of PET Imaging Physics, Chemistry, and Regulations Second Edition With 72 Illustrations
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Gopal B. Saha, Ph.D. Department of Nuclear Medicine The Cleveland Clinic Foundation Cleveland, OH 44195 USA
ISBN 978-1-4419-0804-9 e-ISBN 978-1-4419-0805-6 DOI 10.1007/978-1-4419-0805-6 Springer New York Dordrecht Heidelberg London Library of Congress Control Number: 2009941060 © Springer Science+Business Media, LLC 2010 All rights reserved. This work may not be translated or copied in whole or in part without the written permission of the publisher (Springer Science+Business Media, LLC, 233 Spring Street, New York, NY 10013, USA), except for brief excerpts in connection with reviews or scholarly analysis. Use in connection with any form of information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed is forbidden. The use in this publication of trade names, trademarks, service marks, and similar terms, even if they are not identified as such, is not to be taken as an expression of opinion as to whether or not they are subject to proprietary rights.
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To my teachers, mentors, and friends
Preface
Since the publication of this book in 2005, the growth of positron emission tomography (PET) and PET/CT modality has been phenomenal with the discovery of efficient detectors and the addition of sophisticated scanners and powerful software. Because of the vast advancement and changes in technology, and also with great appreciation of the success of the first edition, we thought a second edition of the book would be appropriate. The book is revised to again fulfill the needs of nuclear medicine professionals such as physicians, technologists, and residents, along with students for their board examination and training. The contents of the book have been kept at the basic level as was in the first edition. The organization of the book essentially has remained the same. Some chapters have been revised very extensively, while others have only minor changes. No change has been made in Chap. 1 as it is based on basic physics. Extensive revision has been made in Chaps. 2 and 3 to include up-to-date information on detectors, scanners, and data collection. Chapter 4 in the original edition has been divided into Chaps. 4 and 5 to allow for a separate chapter on “Storage, Display, and PACS.” Chapter 6 has been updated with new information on NEMA standards on acceptance tests of PET scanners. New PET radionuclides and the list of current available cyclotrons have been added to Chap. 7. Chapter 8 includes a section on Compounding of PET Radiopharmaceuticals, in addition to several new PET radiopharmaceuticals. New regulations concerning the use of PET radiopharmaceuticals, the licensing of physicians and technologists, and the accreditation of PET f
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