Behavioral Neuroscience of Drug Addiction
Drug addiction is a chronically relapsing mental illness involving severe motivational disturbances and loss of behavioral control leading to personal dev- tation. The disorder af?icts millions of people, often co-occurring with other mental illnesses wit
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C U R R E N T TO P I C S I N B E H AV I O R A L N E U R O S C I E N C E S
1 Behavioral Neuroscience of Drug Addiction David W. Self Julie K. Staley Editors
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Current Topics in Behavioral Neurosciences Series Editors: Mark Geyer, La Jolla, CA, USA Bart Ellenbroek, Hamburg, Germany Charles Marsden, Nottingham, UK
About this series Current Topics in Behavioral Neurosciences provides critical and comprehensive discussions of the most significant areas of behavioral neuroscience research, written by leading international authorities. Each volume offers an informative and contemporary account of its subject, making it an unrivalled reference source. Titles in this series are available in both print and electronic formats. With the development of new methodologies for brain imaging, genetic and genomic analyses, molecular engineering of mutant animals, novel routes for drug delivery, and sophisticated cross-species behavioral assessments, it is now possible to study behavior relevant to psychiatric and neurological diseases and disorders on the physiological level. The Behavioral Neurosciences series focuses on ‘‘translational medicine’’ and cutting-edge technologies. Preclinical and clinical trials for the development of new diagnostics and therapeutics as well as prevention efforts are covered whenever possible.
David W. Self
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Julie K. Staley
Editors
Behavioral Neuroscience of Drug Addiction
Editors Prof. Dr. David W. Self University of Texas Southwestern Medical Center Dept. Psychiatry 5323 Harry Hines Blvd. Dallas TX 75390-9070 USA [email protected]
Julie K. Staley{, Ph.D. Department of Psychiatry Yale University School of Medicine VACHS 116A2 950 Campell Ave. West Haven CT 06516 USA
ISSN 1866-3370 e-ISSN 1866-3389 ISBN 978-3-642-03000-0 e-ISBN 978-3-642-03001-7 DOI 10.1007/978-3-642-03001-7 Springer Heidelberg Dordrecht London New York Library of Congress Control Number: 2009938007 # Springer-Verlag Berlin Heidelberg 2010 This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilm or in any other way, and storage in data banks. Duplication of this publication or parts thereof is permitted only under the provisions of the German Copyright Law of September 9, 1965, in its current version, and permission for use must always be obtained from Springer. Violations are liable to prosecution under the German Copyright Law. The use of general descriptive names, registered names, trademarks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. Product liability: The publishers cannot guarantee the accuracy of any information about dosage and application contained in this book. In every individual case the user must check such information by consulting the relevant litera
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