Bioinformatics and Computational Biology First International Con
This book constitutes the refereed proceedings of the First International on Bioinformatics and Computational Biology, BICoB 2007, held in New Orleans, LA, USA, in April 2007. The 30 revised full papers presented together with 10 invited lectures were car
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Edited by S. Istrail, P. Pevzner, and M. Waterman Editorial Board: A. Apostolico S. Brunak M. Gelfand T. Lengauer S. Miyano G. Myers M.-F. Sagot D. Sankoff R. Shamir T. Speed M. Vingron W. Wong
Subseries of Lecture Notes in Computer Science
Sanguthevar Rajasekaran (Ed.)
Bioinformatics and Computational Biology First International Conference, BICoB 2009 New Orleans, LA, USA, April 8-10, 2009 Proceedings
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Series Editors Sorin Istrail, Brown University, Providence, RI, USA Pavel Pevzner, University of California, San Diego, CA, USA Michael Waterman, University of Southern California, Los Angeles, CA, USA Volume Editor Sanguthevar Rajasekaran University of Connecticut, Department of Computer Science and Engineering 257 ITE Building, 371 Fairfield Way, Storrs, CT 06269-2155, USA E-mail: [email protected]
Library of Congress Control Number: Applied for
CR Subject Classification (1998): H.2.8, J.3, I.5, I.2, H.3, F.1-2 LNCS Sublibrary: SL 8 – Bioinformatics ISSN ISBN-10 ISBN-13
0302-9743 3-642-00726-0 Springer Berlin Heidelberg New York 978-3-642-00726-2 Springer Berlin Heidelberg New York
This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, re-use of illustrations, recitation, broadcasting, reproduction on microfilms or in any other way, and storage in data banks. Duplication of this publication or parts thereof is permitted only under the provisions of the German Copyright Law of September 9, 1965, in its current version, and permission for use must always be obtained from Springer. Violations are liable to prosecution under the German Copyright Law. springer.com © Springer-Verlag Berlin Heidelberg 2009 Printed in Germany Typesetting: Camera-ready by author, data conversion by Scientific Publishing Services, Chennai, India Printed on acid-free paper SPIN: 12633326 06/3180 543210
Preface
This volume presents the proceedings of the First International Conference on Bioinformatics and Computational Biology (BICoB 2009). This conference was supported by the International Society for Computers and Applications (ISCA) and Springer. Computational techniques have already enabled unprecedented advances in modern biology and medicine. This continues to be a vibrant research area with broadening of computational techniques and new emerging challenges. The Bioinformatics and Computational Biology (BICoB) conference has the goal of promoting the advancement of computing techniques and their application to life sciences. The topics of interest include (and are not limited to): – Genome analysis: genome assembly; genome and chromosome annotation, gene finding; alternative splicing; EST analysis and comparative genomics – Sequence analysis: multiple sequence alignment; sequence search and clustering; function prediction, motif discovery, functional site recognition in protein, RNA and DNA sequences – Phylogenetics: phylogeny estimation; models of evolution; comparative biological methods; populati