Biomimetic Lipid Membranes: Fundamentals, Applications, and Commercialization

This book compiles the fundamentals, applications and viable product strategies of biomimetic lipid membranes into a single, comprehensive source. It broadens its perspective to interdisciplinary realms incorporating medicine, biology, physics, chemistry,

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metic Lipid Membranes: Fundamentals, Applications, and Commercialization

Biomimetic Lipid Membranes: Fundamentals, Applications, and Commercialization

Fatma N. K¨ok • Ahu Arslan Yildiz • Fatih Inci Editors

Biomimetic Lipid Membranes: Fundamentals, Applications, and Commercialization

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Editors Fatma N. K¨ok Department of Molecular Biology and Genetics ˙ Istanbul Technical University Istanbul, Turkey

Ahu Arslan Yildiz Department of Bioengineering Izmir Institute of Technology Urla, Izmir, Turkey

Fatih Inci School of Medicine Stanford University Palo Alto, CA, USA

ISBN 978-3-030-11595-1 ISBN 978-3-030-11596-8 (eBook) https://doi.org/10.1007/978-3-030-11596-8 Library of Congress Control Number: 2019934721 © Springer Nature Switzerland AG 2019 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Switzerland AG. The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland

To my beloved mother, Nursen Kok – Dr. F. N. Kok To Duru and Hakan, my beloved family, nothing would be possible without their support and encouragement – Dr. A. Arslan Yildiz To my grandparents, S¸ amil – Gülizar Inci and Ne¸set – S¸ ehzade Çiftci, who always believed in my ability to be successful in the academic arena. They are gone but their constant source of support and encouragement have made this journey possible. Regrettably, angels deserve to die . . . – Dr. F. Inci

Preface

The cell, the smallest living unit, interacts with its surroundings via cell membrane and creates a unique biointerface that is vital for cellular processes and cell survival. Better understanding of such a tiny yet complex system is not only crucial for basic research, but also to design advanced platforms for a variety of applications, particularly in medical field. Development of less complex model systems, i.e.,