Biosurveillance and Biosecurity International Workshop, BioSecure 2

This book constitutes the refereed proceedings of the International Workshop on Biosurveillance and Biosecurity, BioSecure 2008, held in Raleigh, NC, USA, in December 2008. The 18 revised full papers presented together with one invited paper were carefull

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Edited by S. Istrail, P. Pevzner, and M. Waterman Editorial Board: A. Apostolico S. Brunak M. Gelfand T. Lengauer S. Miyano G. Myers M.-F. Sagot D. Sankoff R. Shamir T. Speed M. Vingron W. Wong

Subseries of Lecture Notes in Computer Science

Daniel Zeng Hsinchun Chen Henry Rolka Bill Lober (Eds.)

Biosurveillance and Biosecurity International Workshop, BioSecure 2008 Raleigh, NC, USA, December 2, 2008 Proceedings

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Series Editors Sorin Istrail, Brown University, Providence, RI, USA Pavel Pevzner, University of California, San Diego, CA, USA Michael Waterman, University of Southern California, Los Angeles, CA, USA Volume Editors Daniel Zeng MIS Department, University of Arizona Tucson, AZ, USA and Chinese Academy of Sciences E-mail: [email protected] Hsinchun Chen MIS Department, University of Arizona Tucson, AZ, USA E-mail: [email protected] Henry Rolka US CDC, National Center for Public Health Informatics Atlanta, GA, USA E-mail: [email protected] Bill Lober Health Sciences Building, University of Washington Seattle, WA, USA E-mail: [email protected]

Library of Congress Control Number: Applied for CR Subject Classification (1998): J.3, H.2, H.5 LNCS Sublibrary: SL 8 – Bioinformatics ISSN ISBN-10 ISBN-13

0302-9743 3-540-89745-3 Springer Berlin Heidelberg New York 978-3-540-89745-3 Springer Berlin Heidelberg New York

This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, re-use of illustrations, recitation, broadcasting, reproduction on microfilms or in any other way, and storage in data banks. Duplication of this publication or parts thereof is permitted only under the provisions of the German Copyright Law of September 9, 1965, in its current version, and permission for use must always be obtained from Springer. Violations are liable to prosecution under the German Copyright Law. Springer is a part of Springer Science+Business Media springer.com © Springer-Verlag Berlin Heidelberg 2008 Printed in Germany Typesetting: Camera-ready by author, data conversion by Scientific Publishing Services, Chennai, India Printed on acid-free paper SPIN: 12577477 06/3180 543210

Preface

The 2008 Biosurveillance and Biosecurity Workshop (BioSecure 2008) was built on the success of the two U.S. National Science Foundation-sponsored Biosurveillance Workshops. The inaugural 2006 workshop was hosted by the University of Arizona’s NSF BioPortal Center. It attracted more than 35 participants from academic institutions, industry, and public health agencies, and achieved its objective of bringing together infectious disease informatics (IDI) researchers and practitioners to discuss selected topics directly relevant to data sharing and analysis for real-time animal and public health surveillance. The 2007 meeting was held in New Brunswick, New Jersey, co-located with the 2007 IEEE International Conference on Intelligence and Security Informatics, and met with tremendous success. Researchers from a wide ran