Biotransport: Principles and Applications

Biotransport: Principles and Applications is written primarily for biomedical engineering and bioengineering students at the introductory level, but should prove useful for anyone interested in quantitative analysis of transport in living systems.  I

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Robert J. Roselli

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Kenneth R. Diller

Biotransport: Principles and Applications

Robert J. Roselli, Ph.D. Vanderbilt University Dept. Biomedical Engineering Nashville, Tennessee USA [email protected]

Kenneth R. Diller, Sc.D. University of Texas, Austin Dept. Biomedical Engineering Austin, Texas USA [email protected]

ISBN 978-1-4419-8118-9 e-ISBN 978-1-4419-8119-6 DOI 10.1007/978-1-4419-8119-6 Springer New York Dordrecht Heidelberg London Library of Congress Control Number: 2011923229 # Springer ScienceþBusiness Media, LLC 2011 All rights reserved. This work may not be translated or copied in whole or in part without the written permission of the publisher (Springer Science+Business Media, LLC, 233 Spring Street, New York, NY 10013, USA), except for brief excerpts in connection with reviews or scholarly analysis. Use in connection with any form of information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed is forbidden. The use in this publication of trade names, trademarks, service marks, and similar terms, even if they are not identified as such, is not to be taken as an expression of opinion as to whether or not they are subject to proprietary rights. Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com)

Foreword

The science of biotransport embraces the application of a large body of classical engineering knowledge of transport processes to the solution of problems in living systems covering a broad range of phenomena that are essential to homeostasis, and are encountered in routine experiences of human life, or in traumatic, diagnostic, or therapeutic contexts. Analyses of the transport of fluid, heat, and mass have been taught as fundamental components of engineering curricula for many decades, primarily with a focus on applications in industrial processes and design of various types of high-performance devices. The knowledge base that underpins this discipline derives from extensive high-quality, fundamental research conducted over the past century. Consequently, there have been hundreds of textbooks written for the instruction of undergraduates and graduates on the subject of transport processes. In relatively recent times, a new arena of application for transport analysis has arisen dealing with processes in living systems. Although the fundamental physics of the governing transport phenomena remains unchanged, living systems tend to have constitutive properties that are quite distinct from those of typical inanimate systems, including anisotropy, complex geometries, composite materials, nonlinear dependence on state properties, and coupling across multiple energy domains. Therefore, it is important that bioengineering students be able to understand and appreciate the principles and subtleties of transport phenomena in the context of the types of problems that arise in their own field. The subject of biotransport is now widely accepted includi