Blood and Marrow Transplant Handbook Comprehensive Guide for Patient

Developed by the Blood and Marrow Transplant team at Oregon Health & Science University Knight Cancer Institute, this pocket guide provides medical management guidelines for hematopoietic stem cell transplant patients from the moment of their initial

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Blood and Marrow Transplant Handbook Comprehensive Guide for Patient Care Richard T. Maziarz, MD Portland, Oregon, USA

Susan Slater, MN, FNP-BC Portland, Oregon, USA

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Editors Richard T. Maziarz, MD Center for Hematologic Malignancies Adult Blood and Marrow Stem Cell Transplant Program Knight Cancer Institute Oregon Health & Science University Portland, OR 97239, USA

Susan Slater, MN, FNP-BC Center for Hematologic Malignancies Adult Blood and Marrow Stem Cell Transplant Program Knight Cancer Institute Oregon Health & Science University Portland, OR 97239, USA

ISBN 978-1-4419-7505-8 e-ISBN 978-1-4419-7506-5 DOI 10.1007/978-1-4419-7506-5 Springer New York Dordrecht Heidelberg London © Springer Science+Business Media, LLC 2011 All rights reserved. This work may not be translated or copied in whole or in part without the written permission of the publisher (Springer Science+Business Media, LLC, 233 Spring Street, New York, NY 10013, USA), except for brief excerpts in connection with reviews or scholarly analysis. Use in connection with any form of information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed is forbidden. The use in this publication of trade names, trademarks, service marks, and similar terms, even if they are not identified as such, is not to be taken as an expression of opinion as to whether or not they are subject to proprietary rights. While the advice and information in this book are believed to be true and accurate at the date of going to press, neither the authors nor the editors nor the publisher can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the material contained herein. Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com)

Preface and Acknowledgments Hematopoietic stem cell transplantation has experienced a dramatic increase of activity over the past decade with a continued marked escalation of procedures projected over the next ten to fifteen years. This expansion is not only a reflection of an ever changing field with increasing demand but also the pursuit of innovation that contributes to continued improved outcomes with less risk of adverse events or deleterious long-term consequences for the transplant patient population. Cell therapy is a dynamic field. It requires multi-specialty input for the management of these complex patients. In the past, transplantation was the sole responsibility of a few academic centers, and information resided within the hands of a few individuals. However, with the dissemination of technology and the ongoing proliferation of these procedures, there has been an obligatory need for the development of tools to provide standard guidelines and algorithms for the management of patients. Most institutions have established their own set of guidelines and recommendations designed for consensus management as patients are in