Brain Imaging in Behavioral Medicine and Clinical Neuroscience

Brain Imaging in Behavioral Medicine and Clinical Neuroscience Ronald Cohen, editor The question “How does the mind work?” is an enduring one, with new answers appearing on a regular basis. Particularly significant developments in cognition and behavior r

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Ronald A. Cohen  ·  Lawrence H. Sweet Editors

Brain Imaging in Behavioral Medicine and Clinical Neuroscience

Editors Ronald A. Cohen Department of Psychiatry and Human Behavior and the Institute for Brain Science Warren Alpert Medical School of Brown University Providence, RI 02912, USA [email protected] Lawrence H. Sweet Department of Psychiatry and Human Behavior Warren Alpert Medical School of Brown University Providence, RI 02912, USA [email protected]

ISBN 978-1-4419-6371-0 e-ISBN 978-1-4419-6373-4 DOI 10.1007/978-1-4419-6373-4 Springer New York Dordrecht Heidelberg London Library of Congress Control Number: 2010937678 © Springer Science+Business Media, LLC 2011 All rights reserved. This work may not be translated or copied in whole or in part without the written permission of the publisher (Humana Press, c/o Springer Science+Business Media, LLC, 233 Spring Street, New York, NY 10013, USA), except for brief excerpts in connection with reviews or scholarly analysis. Use in connection with any form of information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed is forbidden. The use in this publication of trade names, trademarks, service marks, and similar terms, even if they are not identified as such, is not to be taken as an expression of opinion as to whether or not they are subject to proprietary rights. While the advice and information in this book are believed to be true and accurate at the date of going to press, neither the authors nor the editors nor the publisher can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the material contained herein. Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com)

Foreword

The past two decades have witnessed an explosion of imaging research focused on the human brain. In large part, this growth has been fueled by the emergence of noninvasive, widely available, and relatively low-cost imaging tools that provide precise measurements of brain anatomy and function. The beginning of this era can be tied to the development of functional magnetic resonance imaging (fMRI) in the early 1990s. Prior to this, knowledge of human brain function was derived primarily from the careful study of patients with focal brain lesions. In the decade following its development, fMRI provided the neuropsychologist and cognitive neuroscientist with an implement to validate lesion models by examining brain function in healthy individuals. This trend lead to the development and validation of a wide range of task activation paradigms for probing higher-order cognitive processes, such as language, memory, and attention. As novel and refined models of cognitive systems emerged from fMRI studies of intact individuals, neuroscientists began to apply fMRI to understanding brain disorders. The volume edited by Cohen and Sweet is both unique and timely, since