Neuroscience in Medicine
Continuing progress has been made in understanding the brain at the molecular, anatomic, and physiological levels in the years following the "Decade of the Brain," with the results providing insight into the underlying basis of many neurological disease p
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Medicine Third Edition Edited by
S. Hossein Fatemi, MD, PhD Paula J. Clayton, MD
Edited by
P. Michael Conn
NEUROSCIENCE IN MEDICINE
NEUROSCIENCE IN MEDICINE THIRD EDITION Edited by
P. MICHAEL CONN Oregon National Primate Research Center Oregon Health and Science University Beaverton, OR, USA
Editor Dr. P. Michael Conn Oregon Health & Science University Oregon National Primate Research Center Div. Neuroscience 505 NW 185th Ave. Beaverton OR 97006 USA [email protected]
ISBN: 978-1-60327-454-8
e-ISBN: 978-1-60327-455-5
Library of Congress Control Number: 2008934641 # 2008 Humana Press, a part of Springer ScienceþBusiness Media, LLC All rights reserved. This work may not be translated or copied in whole or in part without the written permission of the publisher (Humana Press, 999 Riverview Drive, Suite 208, Totowa, NJ 07512 USA), except for brief excerpts in connection with reviews or scholarly analysis. Use in connection with any form of information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed is forbidden. The use in this publication of trade names, trademarks, service marks, and similar terms, even if they are not identified as such, is not to be taken as an expression of opinion as to whether or not they are subject to proprietary rights. While the advice and information in this book are believed to be true and accurate at the date of going to press, neither the authors nor the editors nor the publisher can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the material contained herein. Printed on acid-free paper springer.com
PREFACE When the first edition of this book was prepared, we were midway into the ‘‘Decade of the Brain’’—the 1990s. The passage of time has allowed the promise of this field to become the reality of progress. Research in neuroscience and remarkable technology have now made material contributions to human well-being. As in the first two editions, the challenge remained to define the ‘‘core material’’ in a rapidly expanding field. I have continued to restrict peripheral areas (cell function and biosynthesis, for example) in order to focus on emerging and important areas that would not be found in a more generalist text. The book has benefited by supportive contributors who were carefully selected because they are both excellent teachers and academic leaders. That they chose to contribute the time and energy needed for this project is a strong endorsement of their commitment to this discipline and to this project. A substantial number of the authors have been participating since the first edition.
I am pleased to continue the tradition of presenting ‘‘Clinical Correlations’’ for select chapters and that Dr. Greg Cooper has taken over primary responsibility for this task. Because of their popularity, Dr. Cooper has expanded the number of these. Another feature of this edition is the addition of an
